“…Other structural changes associated with the onset of the COVID-19 pandemic include increased awareness of harm reduction principles in the context of the pandemic [59], strained healthcare systems [60,61], decreased access to general health services [62,63], changes in public transportation systems [64], global supply chain interruptions [65], and changes to the illicit drug market with reduced availability of illicit drugs in some settings [66,67]. In addition to these structural changes, there have been many social consequences of the COVID-19 pandemic for PWID, such as resource loss including financial resources and increased social isolation [66,68,69]. Many of these structural and social consequences of the COVID-19 pandemic have also been reported by people who use drugs, including PWID, globally [53,[70][71][72][73][74], highlighting the need to understand the downstream health-related impacts of these changes.…”