Temporal Aspects of Decidual Cell Reaction

Berswordt-Wallrabe, Ilse v.; Geller, H. F.; Herlyn, U.

doi:10.1530/acta.0.0470314

Cited by 4 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is noteworthy, that the addition of ICSH to LGH resulted in a DCR, which was quantitatively comparable with the DCR produced in intact rats receiving LGH alone (v. Berswordt-Wallrabe et al 1964 a and b). Since PMS contains ICSH, it must be assumed, that ICSH is the factor, which enables…”

Section: ) Effects Of Various Gonadotrophic Hormone Combinations In supporting

confidence: 63%

“…352 rats of the FW 49 strain and of the Sprague-Dawley strain were treated under conditions identical to those described by Herlyn et al (1964) with the following 2 exceptions: The stimulus for the DCR-initiation was applied between 10 a. m. and 2 p. m. during day 4 of pseudopregnancy, when the sensitivity to trauma is maximal (v. Berswordt-Wallrabe et al 1964 b) with the exception of 1 group, which was traumatized on day 6. The trauma to the uterus was produced by a knife-tipped needle, as described by De Feo (1963).…”

Section: Methodsmentioning

confidence: 99%

“…1961 a). Daily injections of 1 and 2 mg LGH caused pseudopregnancy in intact rats, which enabled the endometrium to react with DCR following trauma (v. Berswordt-Wallrabe et al 1964 a). These data seem to be in line with those of Evans et al (1941), i. e. that LGH is luteotrophic.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Influence of Gonadotrophic Hormones on the Decidual Cell Reaction in Intact and in Hypophysectomized Rats

Berswordt-Wallrabe¹,

Jantzen²,

Herlyn³

1965

Acta Endocrinologica

Self Cite

View full text Add to dashboard Cite

352 rats were used to study the effects of graded levels of lactogenic hormone (LGH) alone and in combination with PMS and HCG, on the formation of the decidual cell reaction (DCR) in intact and in hypophysectomized rats. Maximal DCR occurred in intact rats and in hypophysectomized rats treated with LGH + HCG and with LGH + HCG + PMS. A marked but significant smaller DCR was found in hypophysectomized rats treated with PMS + LGH. The DCR was absent or very minute in hypophysectomized, LGH-, PMSor HCG-treated rats.The results indicate, that LGH alone is not capable of inducing a DCR.The addition of ICSH to LGH results in an adequate condition for the production of the DCR by uterine trauma. Evans et al. (1941) were the first to show, that their lactogenic preparation from the pituitary gland, containing 30 ILVmg, produced a decidual cell reaction (DCR) in hypophysectomized rats. At a 1 mg level, each of 4 animals showed a DCR response, and at the 0.5 mg level, 2 of 4 animals showed a DCR response. These observations suggested, that the lactogenic and the luteotrophic hormone were identical.It has been shown that graded levels of progesterone are followed by a graded DCR response in ovariectomized rats (v. Berswordt-Wallrabe 8c Turner Herrn Prof. Dr. H. Kirchhoff zum 60. Geburtstag gewidmet. These investigations were supported by Deutsche Forschungsgemeinschaft.

show abstract

Section: ) Effects Of Various Gonadotrophic Hormone Combinations In supporting

confidence: 63%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Influence of Gonadotrophic Hormones on the Decidual Cell Reaction in Intact and in Hypophysectomized Rats

Berswordt-Wallrabe¹,

Jantzen²,

Herlyn³

1965

Acta Endocrinologica

Self Cite

View full text Add to dashboard Cite

show abstract

“…Because in many mammals these gonadotropins are also secreted during progestation, it seems probable that light also may have an influence on the progestational process. Although there is good evidence in support of such activity (14)(15)(16), to date no basic or comprehensive examination has been made of this aspect of reproduction.…”

mentioning

confidence: 99%

Influence of Environmental Lighting on Decidualization in the Rat

Yochim

Mitchell

1970

Endocrinology

View full text Add to dashboard Cite

Adult, virgin Holtzman rats, maintained in a 14-hr light/day photoperiod, were transferred during proestrus to an environment of 2 hr light/day or 22 hr light/day. Pseudopregnancy (Day 0= estrus) was induced upon transfer (0 days pre-exposure, 0 estrous cycles) or following short (1 estrous cycle) or long (5 estrous cycles) pre-exposure to an experimental photoperiod. Decidual sensitivity, assessed after surgical traumatization of the uterus, was measured as uterine weight 5 days post trauma. Sensitivity to decidualization in control animals was absent on midnight of Day 2, but developed rapidly to a peak (2000 mg/cornu) during the interval between midnight of Day 3 and noon of Day 4 of pseudopregnancy. A rapid loss of sensitivity occurred afterward. In relation to controls, 0 and 1 cycle of pre-exposure to 2 hr light/day did not significantly alter the time of onset of decidual sensitivity, though a decreased magnitude of response and a slightly earlier regression were noted. Long pre-exposure to 2 hr light/day resulted in a pattern similar to controls, but somewhat delayed. Pre-exposure for 0 cycles to 22 hr light/day caused a shift in pattern such that sensitivity was reduced significantly from the control on Day 3 midnight but not at noon of Day 4. In animals pre-exposed for 1 estrous cycle, the times of onset and peak responsiveness were delayed about 12 hr. Long pre-exposure delayed further the time of onset of sensitivity and in addition hastened its regression. The data suggest that extended daily illumination may limit decidual sensitivity by increasing endogenous estrogen secretion during early progestation in the rat. (Endocrinology 87: 465, 1970)

show abstract

Deciduomal response of the golden hamster uterus

Harper¹

1969

Anat. Rec.

View full text Add to dashboard Cite

The deciduomal response to uterine trauma in pesudopregnant hamsters has been studied. Trauma was effected in one uterine horn by leaving a sterile silk thread in the lumen, pulling a thread through the lumen, injecting oil or air into the lumen or crushing the horn with a hemostat. At autopsy the traumatized and untraumatized horns were weighed separately and examined histologically for a deciduomal reaction. The day of greatest uterine sensitivity was found to be day 4 of pseudopregnancy, and maximal deciduomal growth (mean uterine weight +-S.E. = 2582 2 279 mg) occurred by day 8. No significant further increase in uterine weight was seen by day 9, and by day 10 separation of the deciduoma from the myometrium had begun. Leaving a thread in the uterine lumen produced a significantly greater uterine weight by day 8 than with any other stimulus, but good deciduomal responses (uterine weights of 1679 2 245, 1255 * 156 and 1192 2 219 mg) were induced by oil injection, pulling a thead through the uterus and crushing the uterus respectively. A poor reponse was produced by air injection. At no particular time during day 4 of pseudopregnancy was it possible to demonstrate a peak of uterine sensitivity using as a traumatic stimulus either oil injection or pulling a thread through the lumen. In this respect hamsters differ from both rats and mice, which have well defined peaks of maximal uterine sensitivity.

show abstract

Temporal Aspects of Decidual Cell Reaction

Cited by 4 publications

References 0 publications

Influence of Gonadotrophic Hormones on the Decidual Cell Reaction in Intact and in Hypophysectomized Rats

Influence of Gonadotrophic Hormones on the Decidual Cell Reaction in Intact and in Hypophysectomized Rats

Influence of Environmental Lighting on Decidualization in the Rat

Deciduomal response of the golden hamster uterus

Contact Info

Product

Resources

About