Template Synthesis of Gold Nanoparticles with an Organic Molecular Cage

McCaffrey, Ryan; Long, Hai; Jin, Yinghua; Sanders, Aric W.; Park, Won; Zhang, Wei

doi:10.1021/ja412606t

Cited by 195 publications

(135 citation statements)

References 50 publications

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“…At ypical methodi st he reduction chloroauric acid (HAuCl 4 )b ys odium borohydride( NaBH 4 )i nt he presence of ligands containing thiol groups, which can significantly stabilize nanoparticles. [7] More recently,t he use of dendrimers, [8] ionic liquids, [9] nucleotides, [10] organic molecular cages, [11] and thiotethered polymers [12] as templates or stabilizers for preparing USGNPs has been reported. Despite the progress achieved, developingafacile and general method to prepare stabilized USGNPs,p articularly with ultrasmall size and tunable surface chemistry,still retains as ignificant challenge.…”

Section: Introductionmentioning

confidence: 99%

In Situ Formation of Dual‐Phase Thermosensitive Ultrasmall Gold Nanoparticles

Zhong

Zhang

et al. 2015

Chemistry A European J

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A novel method for the in situ synthesis of dual-phase thermosensitive ultrasmall gold nanoparticles (USGNPs) with diameters in the range of 1-3 nm was developed by using poly(N-isopropylacrylamide)-block-poly(N-phenylethylenediamine methacrylamide) (PNIPAM-b-PNPEDMA) amphiphilic diblock copolymers as ligands. The PNPEDMA block promotes the in situ reduction of gold precursors to zero-valent gold and subsequently binds to the surface of gold nanoparticles, while PNIPAM acts as a stabilizing and thermosensitive block. The as-synthesized USGNPs stabilized by a thermosensitive PNIPAM layer exhibit a sharp, reversible, clear-opaque transition in aqueous solution between 30 and 38 °C. An unprecedented finding is that these USGNPs also show a reversible soluble-precipitate transition in nonpolar organic solvents such as chloroform at around 0 °C under acidic conditions.

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Section: Introductionmentioning

confidence: 99%

In Situ Formation of Dual‐Phase Thermosensitive Ultrasmall Gold Nanoparticles

Zhong

Zhang

et al. 2015

Chemistry A European J

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“…A recent but alternative approach to prepare nanoparticles is based on the use of synthetic templates which act as molecular cages that are able to block reactions in the nanoscale region [31][32][33]. This process has been successfully applied for preparing HAp nanoparticles using cages of saccharides that are stabilized by strong intermolecular interactions ( Figure 2) [34].…”

Section: Figurementioning

confidence: 99%

Biodegradable and Biocompatible Systems Based on Hydroxyapatite Nanoparticles

et al. 2017

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Abstract:Composites of hydroxyapatite (HAp) are widely employed in biomedical applications due to their biocompatibility, bioactivity and osteoconductivity properties. In fact, the development of industrially scalable hybrids at low cost and high efficiency has a great impact, for example, on bone tissue engineering applications and even as drug delivery systems. New nanocomposites constituted by HAp nanoparticles and synthetic or natural polymers with biodegradable and biocompatible characteristics have constantly been developed and extensive works have been published concerning their applications. The present review is mainly focused on both the capability of HAp nanoparticles to encapsulate diverse compounds as well as the preparation methods of scaffolds incorporating HAp. Attention has also been paid to the recent developments on antimicrobial scaffolds, bioactive membranes, magnetic scaffolds, in vivo imaging systems, hydrogels and coatings that made use of HAp nanoparticles.

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“…For example, lining the pore cavities of a POC with sulfur atoms was shown to anchor and confine Au nanoparticles with controlled diameters and size distributions. 35 Additionally, tuning the porosity of the bulk solid can be achieved by modifying the internal cavities with functional groups of varying steric demand. 36 Given the intensive hostguest studies that have been undertaken in the field of macrocyclic chemistry, functionalization of the internal pore voids is an area of research that is poised for further development.…”

Section: ¹1mentioning

confidence: 99%

Synthesis and Applications of Porous Organic Cages

2015

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Solids composed of shape-persistent organic cage molecules are an emerging class of porous materials. Research in this area has recently progressed from understanding the nature of porosity in these materials to finding applications suited to their unique properties. For example, given that the cages are held together in the solid state by relatively weak (compared to covalent interactions) dispersion forces, the resultant materials are structurally flexible and thus physical properties, such as porosity, that can be modulated according to the adsorbate to which it is exposed. Moreover, discrete cages are soluble and can thus be reprecipitated as structural polymorphs that possess different properties, or processed into thin layers or composite materials such as mixed matrix membranes. In this review, we highlight the synthetic strategies that have been employed to produce porous organic cages and discuss recent advances in design concepts that have led to ultraporous solids. We will also canvass recent applications of these materials and posit potential areas of development.

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Template Synthesis of Gold Nanoparticles with an Organic Molecular Cage

Cited by 195 publications

References 50 publications

In Situ Formation of Dual‐Phase Thermosensitive Ultrasmall Gold Nanoparticles

In Situ Formation of Dual‐Phase Thermosensitive Ultrasmall Gold Nanoparticles

Biodegradable and Biocompatible Systems Based on Hydroxyapatite Nanoparticles

Synthesis and Applications of Porous Organic Cages

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