Abstract:<p>ACTIS
is a new method for finding the equilibrium dissociation constant <i>K</i><sub>d</sub>
of a protein–small molecule complex based on transient incomplete
separation of the complex from the unbound small molecule in a
capillary. This separation is caused by differential transverse
diffusion of the complex and the small molecule in a pressure-driven
flow. The advection-diffusion processes underlying ACTIS can be
described by a system of partial differential equations allowin… Show more
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