“…4,31,83 The AOM rate reects the activities of local microbiota, which are under the control of multiple environmental factors. In addition to the availability of methane and a suitable electron acceptor, other environmental factors, such as temperature, 97,216 pressure, 171,181,216,240 accessibility of essential metal ions, 241 the turnover rate of electron acceptors, 200 organic content, 172,175 etc., have all been documented to affect the AOM rate. It seems that no straightforward model can explain all the observations across different environments due to the different concentrations/levels of these above factors.…”