Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen
Snežana Ilić-Stojanović,
Ljubiša Nikolić,
Vesna Nikolić
et al.
Abstract:The purposes of this study are the polymerization of temperature-sensitive copolymers based on N-isopropyl acrylamide and 10 mol % of 2-hydroxypropylmethacrylate, characterisations of their thermal, morphological and swelling properties, as well as the analysis of potential application in drug-delivery systems. Acetaminophen, the representative of non-steroidal anti-inflammatory drugs, was used as a model drug in this study. It is a common pain relief drug, which is also used for fever treatment. However, oral… Show more
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