Temperature-programmed synthesis of micron-sized multi-responsive microgels

Immobilization of lipase B within micron-sized poly-N-isopropylacrylamide hydrogel particles by solvent exchange

“…S4 12 Meng et al synthesized p-NIPAM microgel particles with acrylic acid as comonomer using the temperature ramp leading to a VPTT of around 31 1C. 30 As known from the literature, the VPTT of p-NIPAM with acrylic acid as comonomer is higher than that of pure p-NIPAM particles. 33 The decreased VPTT of the particles synthesized in the presented work are in good agreement with this investigation.…”

“…30 To investigate the size and the swelling behaviour of the synthesized microgel particles measurements by means of DLS were recorded. The swelling curves for the microgel particles in water and isopropanol are presented in Fig.…”

Synthesis of hybrid microgels by coupling of laser ablation and polymerization in aqueous medium

“…Many studies show that properties such as chemical structure, size, and morphology of nano and microgels can be easily controlled by crosslinking processes such as physical crosslinking, [20][21][22] irradiation-induced crosslinking, [23][24][25] chemical crosslinking based on polyaddition reactions, [26][27][28][29] and polymerization methods (precipitation polymerization [30][31][32][33][34] or miniemulsion polymerization [35][36][37][38][39] ). Based on the typical microgel properties, one can predict the following advantages when using them as microreactors or -carriers in comparison with other template systems: (1) easy preparation; (2) variable size and flexible functionalization by reactive groups; (3) highly porous structure with adjustable degree of crosslinking; (4) enhanced colloidal stability; and (5) stimuli-responsive change of the microgel dimension (T-, pH-sensitivity).…”

Preparation of Responsive Micrometer‐Sized Microgel Particles with a Highly Functionalized Shell

“…Figure 1 a schematically shows the microgel particles' preparation procedure, which combines semi-batch [ 25 ] and a modifi ed temperature-programmed surfactant-free precipitation polymerization [ 26 ] (see Experimental Section for the details). The diameter of the resulting microgels was ∼ 3.3 μ m and the coeffi cient of variation in size was less than 10% (Figure 1 b), indicating that the synthesized microgels were highly monodisperse.…”

“…Under these conditions, the chain propagation rate is higher than the initiation rate, leading to the growth of fewer, large self-crosslinked microgel cores, [ 27 , 28 ] which then serve as a seed for the subsequent polymerization to yield micrometer-sized microgel particles. [ 26 ] To characterize the -COOH group distribution within the resulting microgel particles, we used confocal laser scanning microscopy (CLSM) after labelling the microgel particles with RB at pH 3.5. At this pH, the hydrogen bonding between RB and the carboxylic groups in the microgels can lead to the adsorption of RB into the microgel particles.…”