Temperature influences commensal-pathogen dynamics in a nasal epithelial cell co-culture model
Joshua T. Huffines,
RaNashia L. Boone,
Megan R. Kiedrowski
Abstract:Chronic rhinosinusitis (CRS) is an inflammatory disease of the paranasal sinuses, and microbial dysbiosis associated with CRS is thought to be a key driver of host inflammation that contributes to disease progression.
Staphylococcus aureus
is a common upper respiratory tract (URT) pathobiont associated with higher carriage rates in CRS populations, where
S. aureus
-secreted toxins can be identified in CRS tissues. Although many genera of bacteria colonize the URT… Show more
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