Temperature-induced formation of Pd nanoparticles in heterogeneous nanobiohybrids: application in C–H activation catalysis

Abstract

The effect of the temperature in the synthesis of Pd nanoparticles in the metal-enzyme biohybrids was evaluated. The effect on the formation, size and morphology of the nanoparticles was evaluated...

Preparation of Dual‐activity Enzyme‐metal‐nanoparticles Conjugate Catalysts for Cascade Processes

“…Recently, although the synthetic approach is well described at room temperature, the temperature phenomenon was evaluated in the case of Pd nanobiohybrids. [39] Synthesis at lower T (4 °C) demonstrated that protein structure modification has a major effect on the final PdNPs formation, where lower but smaller nanoparticles were found using C. antarctica B lipase as protein scaffold. The link between protein structure and temperature, as well as the influence of the latter, has been demonstrated to be critical in the reducing capacity of the enzyme in the final Pd nanoparticle production, metal species, and even nanoparticle size.…”

“…Recently, although the synthetic approach is well described at room temperature, the temperature phenomenon was evaluated in the case of Pd nanobiohybrids [39] . Synthesis at lower T (4 °C) demonstrated that protein structure modification has a major effect on the final PdNPs formation, where lower but smaller nanoparticles were found using C. antarctica B lipase as protein scaffold.…”

Palladium nanoparticles for the synthesis of phenanthridinones and benzo[c]chromenes via C–H activation reaction

“…Due to unique properties of Pd NPs such as high reactivity, selectivity, stability and recyclability, the use of Pd nanocatalyst has been extensively investigated in organic synthesis. 50 For instance, Pd NPs were recently explored in C-H bond activation reactions for heterocyclic compounds functionalization, [51][52][53][54][55][56][57][58][59][60][61] or heterocycles synthesis via cyclization reactions. [62][63][64][65] The synthesis of phenanthridine-6(5H)-ones and benzo[c] chromenes by direct arylation reaction catalyzed by Pd NPs was recently reported.…”

Exploring Thermomyces lanuginosus Lipase (TLL)‐PdNPs Nanohybrid as Suitable Catalyst for One‐pot Synthesis of Bis(3‐indolyl)phenylmethane

“…[4,[15][16][17][18][19][20] Recently, the development of a new sustainable synthetic strategy of metal nanoparticles embedded on enzymes as network scaffold has been described and successfully applied in different CÀ C or CÀ H reactions. [21][22][23][24] The advantages of these methods compared to others are the direct use of a heterogeneous catalyst; the control of the nanoparticle size, where the formation is directly induced by the enzyme; the nanoparticles are homogeneously dispersed on the protein network, avoiding aggregation. Thus, the synthetic process of the formation occurs by an initial coordination of the metal ions in solution with specific amino acid residues on the protein structure (i. e., hydrophobic or negatively charged side chains).…”

“…Recently, the development of a new sustainable synthetic strategy of metal nanoparticles embedded on enzymes as network scaffold has been described and successfully applied in different C−C or C−H reactions [21–24] . The advantages of these methods compared to others are the direct use of a heterogeneous catalyst; the control of the nanoparticle size, where the formation is directly induced by the enzyme; the nanoparticles are homogeneously dispersed on the protein network, avoiding aggregation.…”