Temperature‐independent Riboflavineless Mutants of Aspergillus Nidulans

Abstract

Panicker, Radha K., and E. R. B. Shanmugasundaram. (U. Madras, India.) Temperature‐independent riboflavineless mutants of Aspergillus nidulans. Amer. Jour. Bot. 49(6): 555–559. Illus. 1962.—Studies on the biosynthesis of riboflavine using 5 non‐allelic, riboflavineless mutants of Aspergillus nidulans show that: (1) all of them are temperature‐independent; (2) optimal amounts of the vitamin required for maximal growth vary from one mutant to the other; (3) the riboflavine activity of purines and pyrimidines on the mutants are none too different from the earlier observations on Neurospora crassa, Eremothecium ashbyii and Ashbya gossypii; and (4) the isoalloxazine and alloxazine derivatives are not only devoid of vitamin activity but also slightly inhibit the growth of the mutants in presence of the vitamin.