Temperature and the regulation of enzyme activity in poikilotherms. Fructose diphosphatase from migrating salmon

Behrisch, Hans W.

doi:10.1042/bj1150687

Cited by 32 publications

(5 citation statements)

References 27 publications

(34 reference statements)

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“…Unfortunately, tissue profiles of these enzymes have not been estimated for any one fish species, but isolated reports are available: for example, G6Pase in liver and red muscle but not white muscle (flying fish (Shimeno and Ikeda 1967)); FDPase in liver (trout (Behrisch 1969); eel (Vesey, unpublished)) and red and white muscle (dogfish (Crabtree et al 1972); eel (Vesey, unpublished)); PEP CK in liver (trout, eel, lamprey (Phillips and Hird 1977); eel (this paper)), red muscle (dogfish (Crabtree et al 1972)); and PC in liver (trout, eel, lamprey (Phillips and Hird 1977); eel (Renaud, unpublished)) and red muscle (eel (Renaud, unpublished)). Neither PC nor PEP CK have been detected in eel white muscle under the identical conditions where it was found in liver and red muscle.…”

Section: Discussionmentioning

confidence: 98%

The potential for lactate utilization by red and white muscle of the eel Anguilla rostrata L.

Hulbert¹,

Moon²

1978

Can. J. Zool.

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The activities of lactate dehydrogenase (LDH) (L-lactate: NAD+ oxidoreductase, EC 1.1.1.27) can be divided into a lactate oxidase (lactate to pyruvate) and pyruvate reductase (pyruvate to lactate) component. These activities were examined in red and white muscle excised from the American eel Anguilla rostrata as an estimate of tissue lactate utilization, and compared with the kidney, gill, heart, and liver patterns. Phosphoenol pyruvate carboxykinase (PEP CK) activities in red and white muscle and liver were estimated as a marker for tissue gluconeogenic potential. Consistent with the possibility of lactate utilization for gluconeogenesis, both red muscle and liver possessed an active PEP CK and a bifunctional LDH, where oxidase activities were of the same magnitude as reductase activities. Kidney, which in mammals possesses gluconeogenic capabilities, together with heart and gill, also demonstrated LDH profiles consistent with the liver and red muscle enzymes. White muscle LDH was found to be essentially a pyruvate reductase and no PEP CK activity could be detected. These results suggest that eel red muscle has the potential to utilize lactate and has at least some of the enzymes required for gluconeogenesis. Therefore, the capacity of red muscle to perform a metabolic recycling function in addition to contraction cannot be excluded.

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Section: Discussionmentioning

confidence: 98%

The potential for lactate utilization by red and white muscle of the eel Anguilla rostrata L.

Hulbert¹,

Moon²

1978

Can. J. Zool.

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“…In many cases complex U-shaped Km-temperature curves can be shown to be due to the presence of more than one isoenzyme, each having a different affinity for its substrate. This has been shown to be true for lactate dehydrogenases , pyruvate kinases ), fructose diphosphatases (Behrisch, 1969) and isocitrate dehydrogenases (Moon & Hochachka, 1971). Changes in the affinity of choline acetyltransferase for its substrates could be explained by the presence of more than one isoenzyme, but this seems unlikely.…”

Section: Discussionmentioning

confidence: 99%

Effect of environmental temperature on the kinetic properties of goldfish brain choline acetyltransferase

Hebb

Stephens

Smith

1972

Biochemical Journal

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1. Michaelis constants of goldfish brain choline acetyltransferase were found to depend on the concentration of the second substrate present and on the temperature to which the fish had been adapted. 2. Primary plots constructed from results obtained with enzyme prepared from cold-adapted or warm-adapted fish indicated that synthesis of acetylcholine took place by a sequential mechanism. 3. The affinity of choline acetyltransferase for acetyl-CoA was about 100 times that for choline irrespective of whether the enzyme had been prepared from warm-adapted or cold-adapted fish. 4. The maximum rate at which choline acetyltransferase synthesized acetylcholine and the energy of activation for this synthesis remained independent of the previous environmental temperature of the fish. 5. The affinity of choline acetyltransferase for choline and acetyl-CoA showed a complex dependence on temperature. The affinity of the enzyme from cold-adapted fish for substrates increased as the incubation temperature was lowered, whereas that of the enzyme from warm-adapted fish first increased and then decreased. 6. The maximum affinity of choline acetyltransferase for both substrates, from both cold-adapted and warm-adapted fish, occurred at temperatures that corresponded approximately to the respective environmental temperatures of the fish. 7. These changes in enzyme affinity for substrates are not thought to be due to the presence of isoenzymes. Their adaptive significance is unknown, but it could be connected with the maintenance of the enzyme in a stable form.

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“…1) [18], [21], [34], [36]. The fundamental assumption is that a single control enzyme regulates poikilothermic development and the reaction rate of this enzyme affects and determines the rate of development of the organism (here, Anopheles ) [34], [36], [45], [46]. …”

Section: Methodsmentioning

confidence: 99%

ANOSPEX: A Stochastic, Spatially Explicit Model for Studying Anopheles Metapopulation Dynamics

et al. 2013

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Anopheles mosquitoes transmit malaria, a major public health problem among many African countries. One of the most effective methods to control malaria is by controlling the Anopheles mosquito vectors that transmit the parasites. Mathematical models have both predictive and explorative utility to investigate the pros and cons of different malaria control strategies. We have developed a C++ based, stochastic spatially explicit model (ANOSPEX; Ano phelesSpatially-Explicit) to simulate Anopheles metapopulation dynamics. The model is biologically rich, parameterized by field data, and driven by field-collected weather data from Macha, Zambia. To preliminarily validate ANOSPEX, simulation results were compared to field mosquito collection data from Macha; simulated and observed dynamics were similar. The ANOSPEX model will be useful in a predictive and exploratory manner to develop, evaluate and implement traditional and novel strategies to control malaria, and for understanding the environmental forces driving Anopheles population dynamics.

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Temperature and the regulation of enzyme activity in poikilotherms. Fructose diphosphatase from migrating salmon

Cited by 32 publications

References 27 publications

The potential for lactate utilization by red and white muscle of the eel Anguilla rostrata L.

The potential for lactate utilization by red and white muscle of the eel Anguilla rostrata L.

Effect of environmental temperature on the kinetic properties of goldfish brain choline acetyltransferase

ANOSPEX: A Stochastic, Spatially Explicit Model for Studying Anopheles Metapopulation Dynamics

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