Temperature and pH responsive polymers based on chitosan: Applications and new graft copolymerization strategies based on living radical polymerization

Pharmacokinetics and biodegradation performance of a hydroxypropyl chitosan derivative

“…Due to its biocompatibility and biodegradability, chitosan has been widely used in a broad range of areas, such as material, medicine, food and agriculture (Dutta et al, 2009;Honarkar and Barikani, 2009;Pillai et al, 2009;Carreira et al, 2010). Nevertheless, poor solubility of chitosan in neutral solutions greatly limited its applications (Nishimura et al, 1991;Park et al, 2003).…”

Synthesis and characterization of graft copolymers of N-Vinyl-2-Pyrrolidone onto guar gum for sorption of Fe2+ and Cr6+ ions

“…Among the methods of modification of polymers, grafting is one of the promising methods to impart a variety of functional groups to a polymer. Literature survey reveals that recently a good amount of work has been carried out on grafting of various vinyl monomers onto various backbone polymers using different initiating systems (Al-Karawi, Ai-Qaisi, Abdullah, Al-Mokaram, & Al-Heetimi, 2011;Carreira, Gonç alves, Mendonç a, Gil, & Coelho, 2010;Kumar, Singh, & Ahuja, 2009;Saboktakin, Maharramov, & Ramazanov, 2009;Sand, Yadav, & Behari, 2010;Sharma & Mishra, 2010;Singh, Chauhan, Kumar, & Chauhan, 2007;Singha & Rana, 2010;Ye et al, 2010;Zhang et al, 2009). Guar gum is a high molecular weight hydrocolloidal hetero-polysaccharide composed of galactan and mannan units.…”

Development and Characterization of Stimulus-Sensitive Nano/Microparticles for Medical Applications

“…Antibiotics required for treating this disease must therefore be able to retain their activity in acidic gastric juice as well as permeate the mucous layer to reach the bacteria for an effective treatment. Chitosan is a naturally derived pH-responsive polymer with multiple attractive properties such as biocompatibility, mucoadhesiveness, abundance, and biodegradability, among others [7]. Lin et al [8] have recently developed pH-responsive NPs using chitosan and heparin for anti-H. pylori therapy.…”