Temperament and Depression After a First Acute Coronary Syndrome

Ossola, Paolo; Generali, Irene; Schito, Graziana; Panfilis, Chiara De; Tonna, Matteo; Gerra, Maria Lidia; Marchesi, Carlo

doi:10.1097/nmd.0000000000000964

Cited by 4 publications

(2 citation statements)

References 54 publications

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“…As a variety of factors, among which the severity of OCS, might be at play, creating a dichotomy in people with and without OCS hampers the investigation of OCS severity and other moderating factors. Although some of the studies evaluated the association between dimensional measures [ 24 , 50 , 61 , 62 , 66 ], most used a categorical approach. Future studies should aim at using methods that allows to capture the complexity of this issue, for which a dimensional approach appears to be the most suitable option available.…”

Section: Discussionmentioning

confidence: 99%

Meta-analysis of cognitive functioning in patients with psychotic disorders and obsessive–compulsive symptoms

Dijkstra

Vermeulen

Haan

et al. 2020

Eur Arch Psychiatry Clin Neurosci

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Obsessive-compulsive symptoms (OCS) in psychotic disorders are associated with unfavorable outcomes, whether this extends to cognitive function remains unclear. We conducted meta-analyses on several cognitive domains to investigate overall group differences between patients with a psychotic disorder and co-occurring OCS (OCS +) and those without OCS (OCS−). We used meta-regression to assess possible confounding effects. No overall associations between OCS + and OCS− in any of the 17 investigated cognitive domains were found. We predominantly found large heterogeneity in effect size and direction among studies. Post-hoc analyses of processing speed tasks not purely based on reaction-time showed worse performance in the OCS + group with a small effect size (SMD = − 0.190; p = 0.029). Meta-regression revealed advanced age was significantly correlated with worse performance of the OCS + group in processing speed (R 2 = 0.7), working memory (R 2 = 0.11), cognitive inhibition (R 2 = 0.59), and cognitive flexibility (R 2 = 0.34). Patients fulfilling the criteria for an obsessive-compulsive disorder showed less impairment in cognitive inhibition compared to the OCS + group (R 2 = 0.63). Overall, comorbid OCS were not associated with cognitive impairment. However, large heterogeneity between studies highlights the complex nature of factors influencing cognition in people with psychotic disorder and comorbid OCS and warrants further research into possible moderating factors.

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Section: Discussionmentioning

confidence: 99%

Meta-analysis of cognitive functioning in patients with psychotic disorders and obsessive–compulsive symptoms

Dijkstra

Vermeulen

Haan

et al. 2020

Eur Arch Psychiatry Clin Neurosci

View full text Add to dashboard Cite

show abstract

“…На уровень проявления депрессии при ОКС также могут оказывать влияние некоторые социальные факторы, к примеру потеря супруга или проживание без партнера, небольшой материальный достаток или низкий уровень образования [48]. Особенности характера или темперамента человека также могут оказывать некоторое влияние на возникновение депрессии после ОКС [49].…”

Section: особенности проявления депрессии на фоне окс в разных группа...unclassified

Coronary heart disease and depressive disorders, pathogenesis and actual features of the relationship

et al. 2022

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In the conditions of the existing pandemic, that affects both the physical and psychological health of people, it can be predicted with a high degree of probability an outbreak in mental disorders and stress-associated mental illnesses, including depression. The problem of the relationship between depression and cardiac diseases, in particular coronary heart disease (CHD), has been studied by native and foreign scientists for several decades. Various mechanisms have been found and continue to be studied, indicating that the presence of depression can affect more or less on the course of coronary heart disease and even become a predictor of new cardiac events. Dysfunction of the autonomic nervous system with changes in heart rate variability, hyperactivity of the hypothalamic-pituitary-adrenal axis and associated hypercortisolemia, disorders of serotonergic signal transmission pathways, high aggregation response and increased platelet activity, continuous increase of proinflammatory cytokines ((IL17A, IL6, TNFa and IL12p70) in patients’ plasma – such mechanisms probably underlie the correlation between depression and an increased risk of cardiovascular complications and cardiac death. The review includes some features of depression and its influence on various forms of coronary heart disease, particularly in different age and gender groups. In view of the ongoing COVID-19 pandemic, this theme seems to be relevant and requires targeted study. Probably it is necessary to conduct clinical researches, to create registers for a detailed assessment of the mutual influence of depression and coronary heart disease in existing conditions. Perhaps, the results of such work will contribute not only to the early detection and treatment of depression, but also to the development of new ways in primary and secondary prevention of coronary heart disease and its acute forms.

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Psychopathology, Personality and Depression after Acute Coronary Syndrome: A Network Analysis in an Italian Population

et al. 2023

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Several biopsychosocial factors are associated with the onset of a Major Depressive Episode (MDE) after cardiovascular events. However, little is known of the interaction between trait- and state-like symptoms and characteristics and their role in predisposing cardiac patients to MDEs. Three hundred and four subjects were selected among patients admitted for the first time at a Coronary Intensive Care Unit. Assessment comprised personality features, psychiatric symptoms and general psychological distress; the occurrences of MDEs and Major Adverse Cardiovascular Events (MACE) were recorded during a two-year follow-up period. Network analyses of state-like symptoms and trait-like features were compared between patients with and without MDEs and MACE during follow-up. Individuals with and without MDEs differed in sociodemographic characteristics and baseline depressive symptoms. Network comparison revealed significant differences in personality features, not state-like symptoms: the group with MDEs displayed greater Type D personality traits and alexithymia as well as stronger associations between alexithymia and negative affectivity (edge differences between negative affectivity and difficulty identifying feelings was 0.303, and difficulty describing feelings was 0.439). The vulnerability to depression in cardiac patients is associated with personality features but not with state-like symptoms. Personality evaluation at the first cardiac event may help identify individuals more vulnerable to development of an MDE, and they could be referred to specialist care in order to reduce their risk.

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Temperament and Depression After a First Acute Coronary Syndrome

Cited by 4 publications

References 54 publications

Meta-analysis of cognitive functioning in patients with psychotic disorders and obsessive–compulsive symptoms

Meta-analysis of cognitive functioning in patients with psychotic disorders and obsessive–compulsive symptoms

Coronary heart disease and depressive disorders, pathogenesis and actual features of the relationship

Psychopathology, Personality and Depression after Acute Coronary Syndrome: A Network Analysis in an Italian Population

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