Temperament and character profile in failed back surgery syndrome: a cross-sectional clinical study

Yalbuzdağ, Şeniz Akçay; Erol, Asiye Mukaddes; Şengül, İlker; Çelik, Canan; Solum, Sezin; Adilay, Huseyin Utku; Güngör, Buket Belkız

doi:10.5137/1019-5149.jtn.13679-14.0

Cited by 6 publications

(12 citation statements)

References 31 publications

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“…Individuals going through orthognathic surgery, who are more concerned with esthetic aspects than others, may have psychological problems. [1][2][3][4][5] Our study seems to confirm the results in the literature, with 14 of 33 patients who presented parameters that were suggestive of personality (borderline, compulsive, antisocial, and passive-aggressive) disorders.…”

Section: Discussionsupporting

confidence: 85%

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] The suggestion of a 6-month postsurgical phase is because of the fact that, within this period, edema decreases, allowing better visualization of esthetic facial and oral function changes, and the patient returns to social interaction. [1][2][3][4][5] Our choice to perform an assessment at 4 weeks postoperatively (T1) was because of our will to verify, in the immediate postoperative time, an eventual worsening of quality of life, self-esteem, or depression. In fact, the immediate postoperative phase could represent the most ''difficult'' and challenging part of the whole orthognathic treatment to the patient, who has to deal with pain, edema, intermaxillary elastic bands, and so on.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9][10] Preoperatively, orthognathic patients often have psychosocial problems [1][2][3][4][5][6][7][8] so that patients' motivation for the surgical option is usually the hope for improvement of their quality of life. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] However, there is a wide debate about the variation of depressive symptoms, anxiety, and psychosocial well-being after orthognathic surgery. This feature of orthognathic treatment is crucial because the information about the psychosocial effect of orthognathic surgery on patients may allow surgeons to appropriately inform patients regarding their expectations from surgery.…”

mentioning

confidence: 99%

“…This feature of orthognathic treatment is crucial because the information about the psychosocial effect of orthognathic surgery on patients may allow surgeons to appropriately inform patients regarding their expectations from surgery. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] ''Traditional'' 3-stage orthognathic treatment made up of preoperative orthodontics, surgery, and postoperative orthodontics remains a well-established and valid protocol nowadays. Nevertheless, some disadvantages of having orthodontic interventions both before and after orthognathic surgery exist, such as long treatment times, an increased risk of enamel decalcification, gingival recession, and root resorption.…”

mentioning

confidence: 99%

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Psychodynamic Features Associated With Orthognathic Surgery: A Comparison Between Conventional Orthognathic Treatment and “Surgery-First” Approach

Brucoli

Zeppegno

Benech

et al. 2019

Journal of Oral and Maxillofacial Surgery

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Psychodynamic Features Associated With Orthognathic Surgery: A Comparison Between Conventional Orthognathic Treatment and “Surgery-First” Approach

Brucoli

Zeppegno

Benech

et al. 2019

Journal of Oral and Maxillofacial Surgery

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“…Severity and continuity are common characteristics of neuropathic pain (Thomson & Jacques, ). Although great advances have been made, a lot of patients still experience chronic pain, which can result in psychological problems (Monlezun et al, ; Yalbuzdag et al, ). Moreover, the molecular mechanism of neuropathic pain remains unclear.…”

Section: Introductionmentioning

confidence: 99%

XIST accelerates neuropathic pain progression through regulation of miR‐150 and ZEB1 in CCI rat models

Yan

Wang

et al. 2018

Journal Cellular Physiology

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LncRNAs are reported to participate in neuropathic pain development. LncRNA X-inactive specific transcript (XIST) is involved in the progression of various cancers. However, the role of XIST in neuropathic pain remains unclear. In our present study, we established a chronic constriction injury (CCI) rat model and XIST was found to be greatly upregulated both in the spinal cord tissues and in the isolated microglias of CCI rats. Inhibition of XIST inhibited neuropathic pain behaviors including mechanical and thermal hyperalgesia. Moreover, decrease of XIST repressed neuroinflammation through inhibiting COX-2, tumor necrosis factor (TNF)-α and IL-6 and in CCI rats. Previously, miR-150 has been reported to restrain neuropathic pain by targeting TLR5. Currently, miR-150 was predicted to be a microRNA target of XIST, which indicated a negative correlation between miR-150 and XIST. miR-150 was remarkably decreased in CCI rats and overexpression of miR-150 can significantly suppress neuroinflammation-related cytokines. Furthermore, ZEB1 was exhibited to be a direct target of miR-150 and we found it was overexpressed in CCI rats. Silencing ZEB1 was able to inhibit neuropathic pain in vivo and downreguation of XIST decreased ZEB1, which can be reversed by miR-150 inhibitors. Taken these together, we indicated that XIST can induce neuropathic pain development in CCI rats via upregulating ZEB1 by acting as a sponge of miR-150. It was revealed that XIST/miR-150/ZEB1 axis can be provided as a therapeutic target in neuropathic pain.

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Trends of Co-Morbid Depression in Hospitalized Patients with Failed Back Surgery Syndrome: An Analysis of the Nationwide Inpatient Sample

et al. 2018

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IntroductionCo-morbid depression has been associated with poor outcomes following spine surgery and worsening of low back pain symptoms leading to failed back surgery syndrome (FBSS). Given the increasing focus of healthcare utilization and value-based care, it is essential to understand the demographic and economic data surrounding co-morbid depression amongst patients with FBSS.MethodsOur study investigated the NIS database for FBSS patients who had co-morbid depression (ICD-9 CM codes 300.4, 301.12, 309.0, 309.1, 311; ICD-10 M96.1) between 2011 and 2015 across 44 states. We obtained demographic and economic data such as age, sex, ethnicity, location, number of in-patient procedures, hospital length of stay, cost of hospital stay, and frequency of routine discharge dispositions. The NIS database represents approximately a 20% sample of discharges from hospitals in the United States. These data are weighted to provide national estimates for the total United States population. National administrative databases (NADs) like National Inpatient Sample (NIS) are a common source of data for spine procedures. This database is appealing to investigators because of ease of data access and large patient sample. The NIS database is a de-identified database that consists of a collection of billing and diagnostic codes used by participating hospitals with the goal of quality control, population monitoring, and tracking procedures. The NIS does not require institutional review board (IRB) approval or exempt determination.ResultsBetween 2011 and 2015, a total number of 115,976 patients with FBSS were identified. Of these patients, about 23,425 had co-morbid depression. The rate of co-morbid depression in 2015 was 23% with the lowest reported rate being 20% in 2011. Females and Caucasians had consistently higher rates of co-morbid depression compared to males and other ethnic groups respectively. The average length of stay for patients with co-morbid depression fluctuated between 2011 and 2015, with the highest reported at 4.81 days in 2015. The number of procedures increased steadily from 2011 to 2015 with a dip in 2013. The highest number of procedures was reported as 3.94 in 2015. The mean total hospital charges remained stable over time with the largest change being the decrease from 2011 (mean $93,939; 95% CI $80,064–$107,815) to 2012 (mean 82,603; 95% CI $75,127–$90,079). Additionally, patients with FBSS and co-morbid depression were more often discharged home than home with healthcare or to another healthcare facility.ConclusionsThe occurrence of co-morbid depression in hospitalized patients with FBSS increased from 20% in 2011 to 23% in 2015. While direct hospital costs and length of stay remained relatively stable, the number of inpatient procedures performed trended upwards. The exact etiology for this increase in depression prevalence is unknown; additional studies are needed to shed further insight.

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Temperament and character profile in failed back surgery syndrome: a cross-sectional clinical study

Cited by 6 publications

References 31 publications

Psychodynamic Features Associated With Orthognathic Surgery: A Comparison Between Conventional Orthognathic Treatment and “Surgery-First” Approach

Psychodynamic Features Associated With Orthognathic Surgery: A Comparison Between Conventional Orthognathic Treatment and “Surgery-First” Approach

XIST accelerates neuropathic pain progression through regulation of miR‐150 and ZEB1 in CCI rat models

Trends of Co-Morbid Depression in Hospitalized Patients with Failed Back Surgery Syndrome: An Analysis of the Nationwide Inpatient Sample

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