Temperament and character in patients with bipolar II disorder and recurrent brief depression

Lövdahl, H.; Bøen, Erlend; Falkum, Erik; Hynnekleiv, Torfinn; Malt, Ulrik Fredrik

doi:10.1016/j.comppsych.2010.03.003

Cited by 13 publications

(7 citation statements)

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The high values in harm avoidance observed in our study in bipolar patients with respect to healthy controls are consistent with findings in numerous studies with different types of bipolar patients: euthymic patients and patients that remain symptomatic or are in the process of recovery [2], [3], [5], [6], [7], [22], [23], [24], [25], [26], [27]. Although some authors have not found this higher value in the harm avoidance dimension of euthymic bipolar patients [4], [28], other authors have observed this temperamental characteristic even when using different versions of the TCI.…”

Section: Discussionsupporting

confidence: 92%

“…The size of our study is small but similar to those of other studies that have detected associations between personality and BD [4], [25] or between personality and genotype [41], [57]. Table 4 shows a comparison of several studies that have reported differences in personality between bipolar patients and healthy controls; our sample is smaller than most of these studies but has the advantage of being homogenous in terms of diagnosis and clinical state.…”

Section: Discussionsupporting

confidence: 54%

“…In our study, persistence shows a lower value in BD patients. In some other studies, no significant differences are found when comparing the patient and control group [2], [5], [7], [22], [24], [25], [27], [28], although some findings do coincide with ours [3], [4], [6]. Differences in methodologies can explain these discrepancies, such as the type of interview that was used to evaluate personality.…”

Section: Discussionmentioning

confidence: 80%

See 2 more Smart Citations

The Influence of the Val158Met Catechol-O-Methyltransferase Polymorphism on the Personality Traits of Bipolar Patients

Dávila¹,

Basterreche

Arrúe³

et al. 2013

PLoS ONE

View full text Add to dashboard Cite

IntroductionCertain personality traits and genetic polymorphisms are contributing factors to bipolar disorder and its symptomatology, and in turn, this syndrome influences personality. The aim of the present study is to compare the personality traits of euthymic bipolar patients with healthy controls and to investigate the effect of the catechol-O-methyltransferase (COMT) Val158Met genotype on those traits. We recruited thirty seven bipolar I patients in euthymic state following a manic episode and thirty healthy controls and evaluated their personality by means of the Cloninger’s Temperament and Character Inventory (version TCI-R-140). We assessed the influence of the polymorphism Val158Met in the COMT gene on the personality of these patients. The patients scored higher than controls in harm avoidance (61.3±12.5 vs. 55.3±8.1) and self-transcendence (45.3±12.8 vs. 32.7±8.2) and scored lower than controls in self-directedness (68.8±13.3 vs. 79.3±8.1), cooperativeness (77.1±9.1 vs. 83.9±6.5) and persistence (60.4±15.1 vs. 67.1±8.9). The novelty seeking dimension associates with the Val158Met COMT genotype; patients with the low catabolic activity genotype, Met/Met, show a higher score than those with the high catabolic activity genotype, Val/Val.ConclusionsSuffering from bipolar disorder could have an impact on personality. A greater value in harm avoidance may be a genetic marker for a vulnerability to the development of a psychiatric disorder, but not bipolar disorder particularly, while a low value in persistence may characterize affective disorders or a subgroup of bipolar patients. The association between novelty seeking scores and COMT genotype may be linked with the role dopamine plays in the brain’s reward circuits.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 54%

Section: Discussionmentioning

confidence: 80%

See 1 more Smart Citation

The Influence of the Val158Met Catechol-O-Methyltransferase Polymorphism on the Personality Traits of Bipolar Patients

Dávila¹,

Basterreche

Arrúe³

et al. 2013

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Two studies Nowakowska et al, 2005) used the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Autoquestionnaire (TEMPS-A) and found that cyclothymic subscale score was significantly elevated in BP patients. Another study (Lovdahl et al, 2010), which used 5 5 Temperament and Character Inventory (TCI) (Cloninger et al, 1993) to compare bipolar II disorder (BPII) with recurrent brief depression (RBD; defined as intermittent depressive episodes fulfilling the diagnostic criteria for major depressive episodes except for duration, which is less than 14 days), failed to find definitive difference between the two disorders. Evans, et al (Evans et al, 2005) used both TEMPS-A and TCI to find higher dysthymic, cyclothymic, irritable, anxious, and novelty seeking temperaments and lower self-directedness and cooperativeness characters in BP patients.…”

Section: Introductionmentioning

confidence: 99%

Difference in Temperament and Character Inventory scores between depressed patients with bipolar II and unipolar major depressive disorders

Sasayama¹,

Hori²,

Teraishi³

et al. 2011

Journal of Affective Disorders

View full text Add to dashboard Cite

Background: Although some core personality variables are known to be characteristic of unipolar or bipolar depression, few studies have compared the personality profile between these two disorders.Methods: Temperament and Character Inventory (TCI) was employed to assess the personality of 36 depressed patients with bipolar II disorder (BPII), 90 patients with unipolar major depressive disorder (UP), and 306 healthy controls. The TCI was administered during the depressive episode in BPII and UP patients so that the results can be applied in a clinical setting.Results: Significantly higher scores in harm avoidance (pb0.0001) and lower scores in selfdirectedness (pb0.0001) and cooperativeness (pb0.05) were observed in both BPII and UP patients compared to controls. Lower novelty seeking in UP patients compared to BPII patients and controls was observed in females (pb0.0001, pb0.01, respectively).A significant difference in self-transcendence score was observed between BPII and UP patients in females (pb0.0005), with higher scores in BPII (p=0.009) and lower scores in UP (p=0.046) patients compared to controls. A logistic regression model predicted BPII 3 3 in depressed females based on novelty seeking and self-transcendence scores with a sensitivity of 89% and a specificity of 73%, but did not accurately predict BPII in males.Limitations: Patients in our study were limited to those receiving outpatient treatments, and bipolar patients were limited to those with BPII.Conclusions: Novelty seeking and self-transcendence scores of TCI might be useful in the differentiation of UP and BPII in female patients.

show abstract

“…Depression has been with correlated with high HA scores and Low SD scores in the previous studies 35-37. Unlike depression, it has been reported that low RD and C scores are specific to anxiety disorder 38,39.…”

Section: Discussionmentioning

confidence: 84%

The Temperament and Character of Korean Male Conscripts with Military Maladjustment-A Preliminary Study

Han

Lee

2013

Psychiatry Investig

View full text Add to dashboard Cite

ObjectiveRecently, an increasing number of Korean male conscripts have been retiring because of military maladjustment despite the presence of qualifying medical and psychological screening tests in the Korean army. These problems suggest the presence of a common personality problem. To further examine this possibility, the present study used Cloninger's psychobiological model to investigate the temperament and character of soldiers suffering from military maladjustment.MethodsSeventy-nine maladjusted male conscripts and eighty-seven controls enrolled at the 1596th unit from April 2011 to June 2012 participated in the present study. To measure participant personality, we used the Korean version of the Temperament and Character Inventory, Revised-Short. We used logistic regression analysis to examine the association between TCI-RS scores and risk of military maladjustment.ResultsThe maladjustment group had a lower rank, socioeconomic status, education level, and a shorter duration of military service than the control group. The harm avoidance and self-transcendence scores were significantly higher in the maladjustment group, with lower scores for reward dependence, persistence, self-directedness, and cooperativeness scores. However, of these measures, only low cooperativeness was associated with an increased risk of military maladjustment.ConclusionThese results suggest that a low level of cooperativeness can predict military inadequacy. Maladjusted male conscripts may have different personality characteristics from normals. To validate our results, further follow-up or cohort studies with a larger sample will be required.

show abstract

Temperament and character in patients with bipolar II disorder and recurrent brief depression

Cited by 13 publications

References 79 publications

The Influence of the Val158Met Catechol-O-Methyltransferase Polymorphism on the Personality Traits of Bipolar Patients

The Influence of the Val158Met Catechol-O-Methyltransferase Polymorphism on the Personality Traits of Bipolar Patients

Difference in Temperament and Character Inventory scores between depressed patients with bipolar II and unipolar major depressive disorders

The Temperament and Character of Korean Male Conscripts with Military Maladjustment-A Preliminary Study

Contact Info

Product

Resources

About