Telomere Structure in Telomerase Regulation

Analyses of the Life Cycle of TLC1 and the Nuclear RNA Quality Control System in Saccharomyces cerevisiae

“…Besides, the yeast Ku complex contains two proteins, Yku70 and Yku80, playing the central role in the non-homologous end-joining (NHEJ) machinery and the telomere maintenance (Bonetti et al, 2010a;Bonetti et al, 2010b;Gilson et al, 1993; Figure adapted from (Wellinger and Zakian, 2012). Palladino et al, 1993;Porter et al, 1996;Vodenicharov and Wellinger, 2007). The Ku complex participates in tethering the telomeres to the perinuclear region (Martin et al, 1999).…”