Telogen effluvium related to post severe Sars‐Cov‐2 infection: Clinical aspects and our management experience

Rizzetto, Giulio; Diotallevi, Federico; Campanati, Anna; Radi, Giulia; Bianchelli, Tommaso; Molinelli, Elisa; Mazzanti, Sara; Offidani, Annamaria

doi:10.1111/dth.14547

Cited by 51 publications

(91 citation statements)

References 28 publications

(48 reference statements)

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“…In another study conducted using a web-based questionnaire, TE was recorded in 27.9% of 563 individuals, probably as a consequence of mental distress [ 4 ]. Domínguez-Santás et al [ 5 ] were the first to report a case of acute TE, occurring 3 months after SARS-CoV-2 infection, and have been followed by additional authors, who described TE after COVID-19 [ 6 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

Telogen Effluvium after SARS-CoV-2 Infection: A Series of Cases and Possible Pathogenetic Mechanisms

Rossi

Magri

Sernicola

et al. 2021

Skin Appendage Disord

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Introduction: Physicians have largely studied the cutaneous involvement of coronavirus disease 2019 (COVID-19), but only few reports have focused on telogen effluvium (TE) as a possible sequela of COVID-19. We assessed 14 cases of hair loss occurring after SARS-CoV-2 infection using trichoscopy and trichogram to investigate patterns related to COVID-19. Furthermore, we discussed possible mechanisms involved in COVID-19 TE. Case Presentation: Fourteen individuals were referred to our post-COVID-19 dermatology office complaining acute hair loss after SARS-CoV-2 infection. Clinical evaluation included pull test, trichoscopy, and trichogram. COVID-19 TE occurred after a median of 2 months (range 1–3 months) following SARS-CoV-2 infection. The median duration of hair loss was 5 months (range 1–6 months). Trichoscopy showed variable but typical TE patterns. Trichogram showed different telogen/anagen ratio depending on the interval between onset of hair loss and trichological visit. Discussion/Conclusion: Our cases showed TE between 1 and 3 months after the onset of SARS-CoV-2 infection, thus earlier than classic TE. Trichoscopic features and trichogram showed no variations from classic TE. Different pathogenetic mechanisms including pro-inflammatory cytokines and direct viral damage on the hair follicle can be hypothesized; further studies on a larger sample are needed to better understand this condition.

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Section: Discussionmentioning

confidence: 99%

Telogen Effluvium after SARS-CoV-2 Infection: A Series of Cases and Possible Pathogenetic Mechanisms

Rossi

Magri

Sernicola

et al. 2021

Skin Appendage Disord

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“…Although COVID-19 is usually associated with mild to severe respiratory diseases in the acute phase, some patients who recover from COVID-19 complain of dermatologic signs and symptoms such as Hair Loss (HL) several weeks after recovery from the disease. 3 , 4 , 5 , 6 …”

Section: Introductionmentioning

confidence: 99%

“…Acute fever illnesses such as viral infections, including COVID-19, are occasionally involved in the pathogenesis of TE. 6 , 7 , 8 , 9 , 10 , 11 …”

Section: Introductionmentioning

confidence: 99%

Characteristics of telogen effluvium in COVID-19 in western Iran (2020)

Babaei¹,

Kavoussi²,

Rezaei³

et al. 2021

Anais Brasileiros de Dermatologia

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Background Although COVID-19 pandemic significantly induces mortality, many of the patients who recovered present with other medical problems such as alopecias. Telogen effluvium is a common alopecia that is usually related to previous events such as acute febrile diseases, including COVID-19. Objective To evaluate the characteristics of telogen effluvium in COVID-19. Method This cross-sectional study was carried out on 526 patients with documented telogen effluvium that recovered from COVID-19. Demographic data, concurrent alopecia, associated diseases, and COVID-19 severity were recorded. Data were analyzed by appropriate statistical methods. Results The mean age of the 526 patients (410 females, 116 males) was 30.97 ± 9.592 years, with 7.65 ± 1.739 weeks of mean time of alopecia onset. In our patients vitamin D deficiency (24.3%), androgenetic alopecia (78.2%), and grade III disease severity were the most common findings. Alopecia onset was significantly earlier in the younger age group, females, in hypothyroidism, and more severe coronavirus infection. Higher grade coronavirus infection was significantly seen in males, higher ages, earlier onset, and androgenic alopecia. Study limitations Performing a single-center study and considering limited variables. Conclusion Although Coronavirus 2 infection can be an important factor in telogen effluvium induction, other factors such as associated diseases, drug intake and emotional stress may also be involved. In the cases of early onset of alopecia, concomitant diseases such as hypothyroidism and severe coronavirus infections can occur, thus, the presence of various factors in telogen effluvium induction should be considered.

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“…Other forms of hair loss described in COVID-19 patients include telogen effluvium, anagen effluvium, and alopecia areata. [ 59 60 61 ]…”

Section: Cutaneous Manifestations Of Covid-19 Diseasementioning

confidence: 99%

Dermatological manifestations associated with COVID-19 infection

et al. 2021

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Telogen effluvium related to post severe Sars‐Cov‐2 infection: Clinical aspects and our management experience

Cited by 51 publications

References 28 publications

Telogen Effluvium after SARS-CoV-2 Infection: A Series of Cases and Possible Pathogenetic Mechanisms

Telogen Effluvium after SARS-CoV-2 Infection: A Series of Cases and Possible Pathogenetic Mechanisms

Characteristics of telogen effluvium in COVID-19 in western Iran (2020)

Dermatological manifestations associated with COVID-19 infection

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