Telephone-based physical activity counseling for major depression in people with multiple sclerosis.

Abstract

Telephone-based physical activity promotion represents a promising approach to treating MDD in MS. Further research is warranted on ways to bolster the impact of the intervention and on mediators of the treatment effect.

Smoking and Physical Activity: Examining Health Behaviors and 15-Year Mortality Among Individuals With Multiple Sclerosis

“…32 Similarly, brief counseling over several sessions, even when delivered over the telephone, has been shown to improve physical activity. 33 …”

Affective mediators of a physical activity intervention for depression in multiple sclerosis.

“…To evaluate treatment fidelity, 20% of the intervention sessions (n = 65) were randomly selected to be audio recorded and rated. Key indices of MI proficiency including percent open questions, reflections to questions ratio, frequency of Ml-inconsistent behaviors, are reported elsewhere (Bombardier et al, 2013), and suggest an intervention with good fidelity and consistent with the spirit of Ml.…”

A commentary on the importance of controlling for medication use within trials on the effects of exercise on depression and anxiety

“…These details were given in only one multicenter RCT with a large sample (N = 2322) that examined the impact of exercise within a subset of patients with elevated depressive symptoms (Blumenthal et al, 2012b). In the included RCTs, none found an initial difference of baseline antidepressant rate between groups and, only four RCTs carried out their statistical analyses controlling for baseline antidepressant rates (Blumenthal et al, 2012b;Bombardier et al, 2013;Chalder et al, 2012;Gary et al, 2010). Adherence to antidepressant was described in only one investigation (Piette et al, 2011).…”

“…Among participants with depressive disorders the rates of medications at baseline varied between 29% (Gary et al, 2010) and 57% (Chalder et al, 2012;Piette et al, 2011). Among these RCTs, seven included specific participants: patients with heart failure (Gary et al, 2010), postpartum women (Armstrong & Edwards, 2003, adults with multiple sclerosis (Bombardier et al, 2013), adults with diabetes (Piette et al, 2011), primary care patients (Chalder et al, 2012). Among those without depressive disorders, 22% (Blumenthal et al, 2005(Blumenthal et al, , 2012b, 36% (adults with Alzheimer's disease) (Williams & Tappen, 2008) and 20% (Neidig et al, 2003) had medications at baseline.…”

“…The use of antidepressant at baseline was described in 15 RCTs (Armstrong & Edwards, 2003Blumenthal et al, 2005;2012b;Bombardier et al, 2013;Chalder et al, 2012;Chu, Buckworth, Kirby, & Emery, 2009;Craft, Freund, Culpepper, & Perna, 2007;Foley et al, 2008;Gary, Dunbar, Higgins, Musselman, & Smith, 2010;Martinsen et al, 1985Martinsen et al, , 1989Neidig, Smith, & Brashers, 2003;Piette et al, 2011;Veale et al, 1992;Williams & Tappen, 2008). Among participants with depressive disorders the rates of medications at baseline varied between 29% (Gary et al, 2010) and 57% (Chalder et al, 2012;Piette et al, 2011).…”