Técnicas paramétricas de caracterización tisular del miocardio mediante resonancia magnética (parte 2): mapas de T2

Palazon, R. J. Perea; Arqués, M. Solé; González, S. Prat; Robira, T.M. de Caralt; Lopez, M; Pérez, J.T. Ortiz

doi:10.1016/j.rx.2015.05.002

Cited by 5 publications

(3 citation statements)

References 42 publications

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“…However, LGE was slightly overestimated in the actual infarction zone, which may explain for the peri-infarction zone being surrounded by edema after acute myocardial infarction, resulting in increased signal intensity. Of note, LGE has several limitations due to gadolinium dispersion, which is dependent on the time of image acquisition and dose of contrast agent ( 29 , 30 ), which was observed in the process throughout the present study. Thus, in the present investigation, the experimental procedures were performed at 10 min after injection of 0.2 mmol/kg Gd-DTPA.…”

Section: Discussionmentioning

confidence: 86%

Quantitative assessment of salvaged myocardial zone and intramyocardial hemorrhage using non-contrast faster T2 mapping in a rat model by 7T MRI

Zhang

Wang

et al. 2017

Experimental and Therapeutic Medicine

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The aim of this study was to determine the myocardial area at risk (AAR), infarction-core size (IS) and the salvaged myocardial zone (SMZ), and to evaluate the imaging and histological characteristics of intramyocardial hemorrhage (IMH) after myocardial infarction using non-contrast T2 mapping on 7T magnetic resonance imaging (MRI). Twenty Sprague Dawley (SD) rats were randomly divided into the sham and model groups (n=10 in each). In the model group, myocardial infarction models were established by left anterior descending branch ligation. After 24 h, all animals were imaged on a 7.0 Tesla system with cine spiral imaging, T2 mapping with late gadolinium enhancement (LGE). The rats were then sacrificed for measurement of the IS and AAR using 2,3,5-triphenylterazolium chloride (TTC) and hematoxylin and eosin (H&E) staining. T2 mapping revealed that the AAR in the model group was significantly higher than that in the sham group. No remarkable T2 value was noted in the entire heart of the sham group. LGE and TTC staining demonstrated similar IS. T2 mapping and H&E staining revealed a similar AAR as well. T2 mapping characterized the IMH as a phenomenon resulting from the area of hypointensity in the hyperintensity involving the infarct-core zone and corresponding T2 value 928.6±1.52 msec with IMH vs. 35.8±2.61 msec without IMH; n=3 with 18 slices; P=0.032). In conclusion, non-contrast T2 mapping was a reliable approach to quantitatively evaluate the SMZ and IMH.

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Section: Discussionmentioning

confidence: 86%

Quantitative assessment of salvaged myocardial zone and intramyocardial hemorrhage using non-contrast faster T2 mapping in a rat model by 7T MRI

Zhang

Wang

et al. 2017

Experimental and Therapeutic Medicine

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“…Methods for T2 mapping include T2-prepared steady-state free precession (SSFP) [ 32 ], multiecho spin echo (MESE) [ 33 ], and a hybrid of MESE and either turbo spin echo [ 34 ] or gradient spin echo (GraSE) [ 35 ]. The most widely used method is T2-prepared SSFP: to generate a T2 map, a SSFP sequence is used to produce three single-shot T2-weighted images, each of them with a different T2 preparation time (TE T2P ), usually 0 ms, 25 ms, and 55 ms [ 36 ]. The images, acquired in the same cycle phase, in a single apnoea, and in successive heart beats, are obtained every 2 to 4 RR intervals, according to heart rate, in order to achieve sufficient T1 recovery [ 37 ], and then nonrigid movement-correction algorithm is applied to correct residual heart and respiratory movement.…”

Section: Brief Technical Aspectsmentioning

confidence: 99%

Role of CMR Mapping Techniques in Cardiac Hypertrophic Phenotype

et al. 2020

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Non-ischemic cardiomyopathies represent a heterogeneous group of myocardial diseases potentially leading to heart failure, life-threatening arrhythmias, and eventually death. Myocardial dysfunction is associated with different underlying pathological processes, ultimately inducing changes in morphological appearance. Thus, classification based on presenting morphological phenotypes has been proposed, i.e., dilated, hypertrophic, restrictive, and right ventricular cardiomyopathies. In light of the key diagnostic and prognostic role of morphological and functional features, cardiovascular imaging has emerged as key element in the clinical workflow of suspected cardiomyopathies, and above all, cardiovascular magnetic resonance (CMR) represents the ideal technique to be used: thanks to its physical principles, besides optimal spatial and temporal resolutions, incomparable contrast resolution allows to assess myocardial tissue abnormalities in detail. Traditionally, weighted images and late enhancement images after gadolinium-based contrast agent administration have been used to perform tissue characterization, but in the last decade quantitative assessment of pre-contrast longitudinal relaxation time (native T1), post-contrast longitudinal relaxation time (post-contrast T1) and transversal relaxation time (T2), all displayed with dedicated pixel-wise color-coded maps (mapping), has contributed to give precious knowledge insight, with positive influence of diagnostic accuracy and prognosis assessment, mostly in the setting of the hypertrophic phenotype. This review aims to describe the available evidence of the role of mapping techniques in the assessment of hypertrophic phenotype, and to suggest their integration in the routine CMR evaluation of newly diagnosed cardiomyopathies with increased wall thickness.

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“…However, this technique is very sensitive to the various artifacts, induced by irregular heart rate or inabilities to maintain breath-hold. In addition, T2-weighted sequences are unable to detect generalized myocardial edema [ 19 ]. The quantitative T2 mapping overcomes these limitations.…”

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confidence: 99%

Cardiac MRI quantitative tissue characterization of right atrial mass using mDixon and parametric mapping

et al. 2017

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Técnicas paramétricas de caracterización tisular del miocardio mediante resonancia magnética (parte 2): mapas de T2

Cited by 5 publications

References 42 publications

Quantitative assessment of salvaged myocardial zone and intramyocardial hemorrhage using non-contrast faster T2 mapping in a rat model by 7T MRI

Quantitative assessment of salvaged myocardial zone and intramyocardial hemorrhage using non-contrast faster T2 mapping in a rat model by 7T MRI

Role of CMR Mapping Techniques in Cardiac Hypertrophic Phenotype

Cardiac MRI quantitative tissue characterization of right atrial mass using mDixon and parametric mapping

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