We performed an exhaustive compilation of patents involving a CRISPR gene editing system and categorized them following a thorough analysis of their abstract, description and claims. This landscape of CRISPR patenting shows that the technology is constantly being improved and that there is a diversity of potential sectors of application (medical, industrial, agriculture), of actors (both public and private) and a novel geopolitical balance of forces in this crucial new biotechnological field. Although laboratories in the USA played a pioneer role in the original invention, and USA remains a leader in technical improvements and in the medically applied sector, China is now taking the lead in the industrial and agricultural applied sectors and in the total number of patents per year. Strikingly, in all sectors, the number of CRISPR patents originating from Europe trails far behind the USA and China. Korea and Japan are next in this ranking. On August 17, 2012 Jennifer Doudna's group (University of California-Berkeley, USA) and Emmanuelle Charpentier (Umeå University, Sweden; formerly in Vienna, Austria) highlighted the underlying molecular mechanisms of the CRISPR system (Clustered Regularly Interspaced Short Palindromic Repeats) 1. They demonstrated that this system can be used to produce double-stranded cuts at any precise site of DNA in prokaryotic cells by combining a RNA guide with an endonuclease protein (Cas9, CRISPR-associated protein 9 nuclease). Prior to this publication, on May 25, 2012, UC-Berkeley, the University of Vienna and Jennifer Doudna had filed a patent application (2012US-61652086) describing the methods and applications for this RNA-directed site-specific DNA modification. On the other hand, the groups of Feng Zhang at the Broad Institute of MIT and Harvard University, USA 2 and George Church at Harvard University, USA 3 demonstrated that the CRISPR system can be used to modify eukaryotic cells of mammals, including humans. On December 12, 2012, the Broad Institute, MIT and Feng Zhang filed a patent application (2012US-61736527) describing the invention of mammalian genome editing. The legal battles around these patents have attracted media attention (4, 5, Sherkow 2018).