Technology of Immunocorrection at Mental Disorders

Vetlugina, T.P.; Nevidimova, T.I.; Lobacheva, O.A.; Nikitin, V.B.

doi:10.17513/np.103

Cited by 5 publications

(3 citation statements)

References 23 publications

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“…Более подробные сведения о биологии карася в водоемах дельты Волги начали появляться с 1980-х гг. [3][4][5].…”

Section: Introductionunclassified

Comparative characteristics of the silver crucian carp (Carassius auratus gibelio) internal organs state in the age aspect

Grushko,

Terpugova,

Fedorova

2023

Vestnik of Astrakhan State Technical University. Series: Fishing Industry

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The histological results of the study of the organs of larvae and mature individuals of the silver crucian carp Carassius auratus gibelio (Bloch, 1782) caught in the reservoirs of the Volga River delta are presented. Analysis the internal organs state and tissues helps to identify physiological disorders and pathologies. Thanks to the histological method, it becomes possible to study the structure of the body at the cellular and tissue level, to determine the development of the pathological process and the degree of damage. For pathomorphological evaluation, the liver, gills, kidneys, spleen, intestines and pancreas were examined in silver crucian carp of different ages. It was established that representatives of this species of different ages had identical pathological changes in the organs, but the degree of their manifestation was different: there was a tendency to increase the intensity of the pathology with age. 4 types of major pathological changes associated with metabolic disorders, necrotic damage to cells and tissues, circulatory disorders of organs and signs of hyperplasia were found. Sexually mature individuals had a higher level of pathological manifestations. To a greater extent, the gills, which are in direct contact with the environment, were damaged. The liver of the studied fish also had significant damage. The most frequently reported liver pathology was lipoid degeneration (vacuolar degeneration). Kidneys, intestines and spleen were characterized by degenerative and necrotic disorders. In the spleen of adults, granulomatous inflammation was found, which indicates infectious diseases. The same types of morphological changes were found in larvae and mature individuals, which indicates the nonspecific nature of the identified pathologies, which, as a rule, are associated with the adaptation of the organism to the prevailing living conditions.

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“…Более подробные сведения о биологии карася в водоемах дельты Волги начали появляться с 1980-х гг. [3][4][5].…”

Section: Introductionunclassified

Comparative characteristics of the silver crucian carp (Carassius auratus gibelio) internal organs state in the age aspect

Grushko,

Terpugova,

Fedorova

2023

Vestnik of Astrakhan State Technical University. Series: Fishing Industry

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“…At the beginning of the 20th century, representatives of psychomarkism A. Pauli and R. France represented adaptation through the inclusion of the need-motivational sphere of a person's personality to achieve a condition of adaptiveness [5]. In psychological studies of adaptation, the main conceptual approaches to the consideration of the phenomenon of adaptation, in particular psychophysiological, in which it is presented in the form of changes in the environment and changes in the body through actions corresponding to a given situation (R. Hankey) [quote by : 6].…”

Section: Introductionmentioning

confidence: 99%

Problems of social and psychological adaptation of students in conditions of social deprivation

et al. 2021

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The article is devoted to changes in the level of empathy and some structural components of social and psychological adaptation caused by social deprivation in a pandemic, which is the purpose of the work. The paper presents the results of an empirical study conducted in the first semester of the 2020-2021 academic year, when Samara State Technical University students were on distance learning. The sample consisted of 248 first-year students. The basis of the observation is a longitudinal research, during which the communicative activity of students in interaction with the teacher and with each other was recorded. In addition, students solved situational problems containing a description of the conflict, for a way out of which they had to offer solutions: none, one or several. The study confirmed the hypothesis put forward about possible changes in the level of empathy, the ability to solve situational problems and social and psychological adaptation in general among students studying remotely. Isolation in a pandemic is an objective measure for which humanity was not ready.

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“…Следует отметить, что на изменение иммунных показателей при депрессивных расстройствах, включая значительные колебания числа ЕК, оказывают влияние различные факторы, например, такие как тип депрессии, глубина депрессивного аффекта, возраст больного, пол, принадлежность к определенной этнической группе, типологические особенности больных [36,37,38].…”

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Нейроиммунные Механизмы Нейродегенеративных Заболеваний: Роль Цитокинов И Толл-Подобных Рецепторов

2018

СВПН

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Идова Г.В., Альперина Е.Л., Жанаева С.Я. и др. Нейроиммунные механизмы нейродегенеративных заболеваний… Сибирский вестник психиатрии и наркологии. 2018; 2 (99): 99-104 99 ЛЕКЦИИ. ОБЗОРЫ УДК 616.89-008.454:616.858:57.083.3 Для цитирования: Идова Г.В., Альперина Е.Л., Жанаева С.Я., Геворгян М.М. Нейроиммунные механизмы нейродегенеративных заболеваний: роль цитокинов и толл-подобных рецепторов. Сибирский вестник психиатрии и наркологии. 2018; 2 (99): 99-104. https://doi.1 Научно-исследовательский институт физиологии и фундаментальной медицины Россия, 630117, Новосибирск, ул. Тимакова, 4 2 Новосибирский национальный исследовательский государственный университет Россия, 630090, Новосибирск, ул. Пирогова, 2 РЕЗЮМЕ Важная роль нейроиммунных механизмов в патогенезе нейродегенеративных заболеваний, таких как болезнь Паркинсона и депрессия, привлекает особое внимание исследователей. Обзор сфокусирован на данных, свидетельствующих об изменении активности факторов воспаления, включая провоспалительные цитокины и различные типы толл-подобных рецепторов как у пациентов, так и в экспериментальных моделях данных заболеваний. Участвующие в процессе воспаления цитокины и толл-подобные рецепторы могут служить информативными биомаркерами различных патологических состояний и/или мишенью для новых терапевтических подходов их лечения. Ключевые слова: нейроиммунные механизмы, нейровоспаление, цитокины, толл-подобные рецепторы болезнь Паркинсона, депрессивные расстройства. * Идова Галина Вениаминовна, galina-idova@mail.ru УДК 616.89-008.454:616.858:57.083.3 Лекции. Обзоры Siberian Herald of Psychiatry and Addiction Psychiatry. 2018; 2 (99): 99-104 104 For citation: Idova G.V., Alperina E.L., Zhanaeva S.Ya., Gevorgyan M.M. Neuroimmune mechanisms of neurodegenerative disorders: role of cytokines and toll-like receptors. Siberian Herald of Psychiatry and Addiction Psychiatry. 2018; 2 (99): 99-104. ABSTRACTThe important role of neuroimmune mechanisms in the development of neurodegenerative disorders, such as Parkinson's disease and depression gained increasing attention. This review was focused on the data, giving evidence of changing activity of inflammatory factors, including pro-inflammatory cytokines and different types of toll-like receptors, both in patients and animal models of these disorders. Cytokines and toll-like receptors, involved in the process of inflammation, might serve as informative biomarkers of various pathologies and/or as potential targets for new therapeutic strategies.

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Technology of Immunocorrection at Mental Disorders

Cited by 5 publications

References 23 publications

Comparative characteristics of the silver crucian carp (Carassius auratus gibelio) internal organs state in the age aspect

Comparative characteristics of the silver crucian carp (Carassius auratus gibelio) internal organs state in the age aspect

Problems of social and psychological adaptation of students in conditions of social deprivation

Нейроиммунные Механизмы Нейродегенеративных Заболеваний: Роль Цитокинов И Толл-Подобных Рецепторов

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