Technology clinical trials: Turning innovation into patient benefit

Abstract

Health care needs to continuously evolve and innovate to maintain the health of populations. Technology has the potential to enable better patient engagement and ownership, as well as optimise therapeutic interventions and data-science approaches to facilitate improved health care decisions. Yet, to date, technological innovation has not resulted in the rate of change that could have been predicted from other sectors. This article discusses multiple reasons for this and proposes a newly tested and deployed solution: the technology clinical trial. The technology clinical trial methodology has been developed through working directly with patients, clinical and medical devicetrial experts. This approach enables researchers to use the complex environment of health care as an opportunity to transform the pace of innovation and create new care pathways. Instead of testing a single innovation, researchers can ‘step back’ and systematically review all areas of the patient's journey for potential optimization. Then integrate novel data science, technological advances, process updates, behavioural science, and patient engagement to co-create a streamlined multidisciplinary solution. As a result, this research has the potential for larger advances due to the emergent benefits that can arise when the individual elements work together as a whole. These potential benefits are then robustly tested, characterised and measured in the trial environment to ensure that future application of the innovative pathway is supported by the robust empirical data health care requires.

Heart Failure-Smart Life: a randomized controlled trial of a mobile app for self-management in patients with heart failure

“…In particular, considering the pandemic era, such as the COVID-19 pandemic, the availability of non-face-to-face strategies, like mobile apps, will be critical, and their impact on patients who are remaining at home should be investigated. Through further clinical trials using mobile apps, it can expand the potential to give patients with diverse chronic diseases better engagement and ownership of lifelong self-management at home [ 38 ] and enable to meet the expectations of healthcare providers to optimize the patients’ therapeutic adherence in the future.…”