To address the challenges in teaching object-oriented analysis and design, such as abstract course content, limited practical skills among students, difficulty stimulating interest, and difficulty in achieving high-quality and inclusive education, based on an in-depth analysis of the course’s knowledge system and teaching objectives, we proposed an innovative teaching strategy from the perspective of sustainable development. This strategy takes the analysis and design of software projects selected by students as the main focus and teacher case guidance as the entry point, connecting theoretical knowledge and teaching practice, and is called “case guidance multi-project synchronous implementation”. Simultaneously, we reshaped the teaching process and reformed the course assessment to adapt to this new teaching strategy. The results of its implementation show that this strategy not only helped students to better understand and apply object-oriented analysis and design but also enhanced their interest and sense of access to the course, successfully improving the achievement of the course objectives and significantly promoting students’ innovation and practical skills, providing an effective way to achieve high-quality and inclusive education and the promotion of lifelong learning. The successful implementation of this teaching strategy provides a strong reference for teaching reform in similar courses.