Technological Challenges of Pediatric MEG and Potential Solutions: The Aston Experience

Witton, Caroline; Furlong, Paul L.; Seri, Stefano

doi:10.1007/978-3-319-62657-4_30-1

Cited by 1 publication

(1 citation statement)

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“…It is also possible to construct “cortical psychometric functions” from auditory evoked responses measured with neurophysiological data, a method which shows promise for bias-free estimates of threshold (Witton et al, 2012). Yet there are challenges associated with using neuroimaging techniques with children (Witton, Furlong & Seri, 2013) and for the majority of studies, psychophysics will remain the method of choice. Developing strategies to reduce the likelihood of lapses during adaptive procedures, especially through improving task engagement by children (e.g., Abramov et al, 1984), is therefore critical—as is the use of statistical methods which are sensitive to the limitations of these procedures.…”

Section: Discussionmentioning

confidence: 99%

Psychophysical measurements in children: challenges, pitfalls, and considerations

Witton

Talcott

Henning

2017

PeerJ

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Measuring sensory sensitivity is important in studying development and developmental disorders. However, with children, there is a need to balance reliable but lengthy sensory tasks with the child’s ability to maintain motivation and vigilance. We used simulations to explore the problems associated with shortening adaptive psychophysical procedures, and suggest how these problems might be addressed. We quantify how adaptive procedures with too few reversals can over-estimate thresholds, introduce substantial measurement error, and make estimates of individual thresholds less reliable. The associated measurement error also obscures group differences. Adaptive procedures with children should therefore use as many reversals as possible, to reduce the effects of both Type 1 and Type 2 errors. Differences in response consistency, resulting from lapses in attention, further increase the over-estimation of threshold. Comparisons between data from individuals who may differ in lapse rate are therefore problematic, but measures to estimate and account for lapse rates in analyses may mitigate this problem.

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Section: Discussionmentioning

confidence: 99%