Technological and biological evaluation of tablets containing different strains of lactobacilli for vaginal administration

Physicochemical Properties and Excipient Compatibility Studies of Probiotic Bacillus coagulans Spores

“…At relatively low compaction pressure of 1000 psi, assay values for 'cell pellet' and 'diluent mixed cell pellet' were reduced by about 5% but at higher compaction pressures the activity reduced significantly. These results were similar to the previous reports of Maggi et al [8], Fazeli et al [15] and Durand et al [16] for other probiotic lactobacilli. A reduction in the viability of different strains of lactobacilli during manufacture of mono and double layer tablets of freeze dried cultures was reported by Maggi et al Durand and Panes [16] demonstrated that different species of probiotic bacteria had different levels of resistance to compaction pressure.…”

“…Maggi and coworkers [8] studied the viability of lactobacilli incorporated in vaginal tablet. Similarly, the survival of probiotic vaginal lactobacilli in stock cultures has been assessed by J. Tomas et al [9].…”

Development of effervescent products, in powder and tablet form, supplemented with probiotics Lactobacillus acidophilus and Saccharomyces boulardii

“…Maggi et al (2000) also verified a reduction Madureira et al (2005) observed that when pre-incubated in artificial gastric juice for 120 minutes, Lactobacillus acidophilus strain LAC-1 showed a decrease in the number of viable cells by approximately three logarithmic cycles, which also occurred during the 30 minutes of subsequent contact with the bile salts.…”

Evaluation of Mechanical and Mucoadhesive Properties of Clomiphene Citrate Gel Formulations Containing Carbomers and Their Thiolated Derivatives

“…The mucoadhesive formulations, administered by rectal (Choi, Oh, and Kim 1998;Ryu et al 1999;Yahagi, Onishi, and Machida 1999), vaginal (Lee and Chien 1996;Valenta et al 2001;Ceschel et al 2001a;Cevher, Sahin, and Araman 2002;Chang et al 2002;Chien and Lee 2002;El-Kamel et al 2002;Maggi et al 2000), oral (Takeuchi et al 2003), buccal (Shojaei, Zhou, and Li 1998;Alur et al 1999;Han et al 1999;Choi and Kim 2000;Shin, Bum, and Choi 2000;Ceschel, Maffei, and Lombardi 2001b;Perioli et al 2004), nasal (Ugwoke et al 1999;Yahagi et al 2000;Pavelic, SkalkoBasnet, and Schubert, 2001;Hasçiçek, Gönül, and Erk 2003;58 E. CEVHER ET AL. Sales et al 2003), and ocular (Yun et al 1999;Ceulemans et al 2001) routes, have been prepared by using polymers showing appropriate adhesiveness.…”