Techniques of intrauterine fetal transfusion for women with red-cell isoimmunisation for improving health outcomes

Dodd, Jodie M; Windrim, Rory; Kamp, Inge L. van

doi:10.1002/14651858.cd007096.pub3

Cited by 8 publications

(5 citation statements)

References 35 publications

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“…However, caution is necessary when evaluating the present material considering the wide confidence intervals. The benefits and dangers of different techniques of IUT were evaluated in a recent Cochrane report, but the results were inconclusive due to insufficient number of randomized controlled studies [20] . If the umbilical vein in the liver cannot be easily punctured, an alternative could be considered.…”

Section: Discussionmentioning

confidence: 99%

Procedure-Related Complications and Perinatal Outcome after Intrauterine Transfusions in Red Cell Alloimmunization in Stockholm

Tiblad¹,

Kublickas²,

Ajne³

et al. 2011

Fetal Diagn Ther

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Introduction: We present a review of all cases of intravascular transfusions in red cell alloimmunization over a time span of 20 years in Stockholm. The aim of the study is to compare our results with published results from larger centers and to identify areas that can be further improved. Material and Methods: A retrospective cohort study was conducted of all women treated with intrauterine transfusions due to erythrocyte immunization in our hospital between June 1990 and June 2010. Primary outcome variables were fetal and neonatal survival, procedure-related complications and gestational age at delivery. Results: A total of 284 intrauterine transfusions were performed in 84 pregnancies, with an overall survival rate of 91.8%. Procedure-related and fatal complications occurred in the present study in 4.9 and 1.4% of fetuses or neonates, respectively. Procedure-related complications were significantly more common in free-loop transfusions than in transfusions in the intrahepatic part of the umbilical vein (OR: 5.4, p = 0.025). There was no significant difference between the intrahepatic and the placental cord insertion route (p = 0.83). Gestational age at first transfusion was significantly associated with an increased risk of a procedure-related complication (OR: 0.8, p = 0.019). Of the live-born infants, 24% of the neonates were born before gestational week 34. Discussion: Our study confirms previous studies demonstrating favorable results with intravascular transfusions.

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Section: Discussionmentioning

confidence: 99%

Procedure-Related Complications and Perinatal Outcome after Intrauterine Transfusions in Red Cell Alloimmunization in Stockholm

Tiblad¹,

Kublickas²,

Ajne³

et al. 2011

Fetal Diagn Ther

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“…Fetal distress secondary to local cord accidents may be a result of sudden fetal movements and dislodgment of the needle from its intended site. The use of fetal paralysis may prevent procedure-related fetal loss in 80% of the cases and thus improve the safety of the procedure [7,61]. Even more, prevention of volume overload by adjusting transfusion speed to gestational age, especially in young fetuses and/or hydropic fetuses, may improve outcome [25,62].…”

Section: Improving Outcomementioning

confidence: 99%

Intrauterine Blood Transfusion: Current Indications and Associated Risks

Lindenburg

Kamp

Oepkes³

2014

Fetal Diagn Ther

137

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Fetal anemia is a serious complication in pregnancy and associated with perinatal mortality and morbidity. During 25 years of worldwide experience with intravascular intrauterine blood transfusion, a variety of indications have been described. Intrauterine transfusion (IUT) treatment is considered most successful for fetal anemia due to red cell alloimmunization. Moreover, the use of this procedure has also been reported in pregnancies with parvovirus B19 infection, fetomaternal hemorrhage and placental chorioangiomas, for example. This review focuses on the current indications of intrauterine blood transfusions. In addition, we describe the potential complications of IUT treatment.

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“…Elección del lugar de acceso: se prefiere la transfusión intravascular (TIV) a la intraperitoneal, debido a la mayor tasa de supervivencia (18) , y se prefiere la vena umbilical (a nivel de su inserción placentaria) a la arteria umbilical, por su fácil acceso y menor incidencia de bradicardia (17) .…”

Section: Transfusión Intrauterinaunclassified

Anemia fetal, diagnóstico y manejo actual

Huertas

2019

Rev peru ginecol obstet.

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La anemia fetal es una condición poco frecuente en nuestro medio, pero potencialmente letal para el feto, si no se diagnostica y maneja oportunamente. Las causas son diversas, desde autoinmunes (isoinmunización Rh) a infecciosas (parvovirus B19), hemogobinopatías, hemorragia feto materna y complicaciones del embarazo monocoriónico. El diagnóstico puede ser por métodos invasivos (cordocentesis) o no invasivos (pico de velocidad sistólica de la arteria cerebral media – PVS-ACM), aunque se prefiere los últimos. El tratamiento consiste en la transfusión intrauterina, la cual permite sobrevida hasta en 90% de casos, sin secuelas neurológicas. El presente artículo revisa aspectos acerca de la definición, clasificación, causas, diagnóstico y manejo actualizado de la anemia fetal.

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Techniques of intrauterine fetal transfusion for women with red-cell isoimmunisation for improving health outcomes

Cited by 8 publications

References 35 publications

Procedure-Related Complications and Perinatal Outcome after Intrauterine Transfusions in Red Cell Alloimmunization in Stockholm

Procedure-Related Complications and Perinatal Outcome after Intrauterine Transfusions in Red Cell Alloimmunization in Stockholm

Intrauterine Blood Transfusion: Current Indications and Associated Risks

Anemia fetal, diagnóstico y manejo actual

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