Techniques for the Investigation of Age-Related Bone Loss and Osteoporosis in Archaeological Bone

Brickley, Megan

doi:10.1007/978-1-4419-8891-1_10

Cited by 20 publications

(28 citation statements)

References 73 publications

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“…The present research compares the raw data generated in Brickley's study with measurements of metacarpal cortical bone loss undertaken on the same archaeological individuals. The various techniques utilised by Brickley are summarized here (Table 1); for full discussion see Brickley and Agarwal [4], Brickley and Howell [5], Farquharson and Brickley [14,15], Farquharson et al [16] and Brickley [6].…”

Section: Methodsmentioning

confidence: 99%

“…The increasing clinical prevalence is encouraging interest in archaeological research aimed at investigating the extent to which osteoporosis may have existed in past populations [1]. A recent review of the variety of techniques currently available to investigate age-related bone loss and osteoporosis in archaeological human bones considered metacarpal radiogrammetry as a potentially useful, relatively simple and inexpensive technique in assessing cortical bone loss in the past [4]. The technique involves measuring the amount of cortical bone from radiographs.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Metacarpal radiogrammetry: a useful indicator of bone loss throughout the skeleton?

Ives¹,

Brickley²

2005

Journal of Archaeological Science

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Metacarpal radiogrammetry: a useful indicator of bone loss throughout the skeleton?

Ives¹,

Brickley²

2005

Journal of Archaeological Science

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“…Although, strictly speaking, 'osteoporosis' refers to extreme osteopenia, it is now more commonly used to describe the abnormally low quantity and impaired architectural arrangement of bone tissue generally associated with older bones (Gallagher, 1990;Melton et al, 1992;Brickley & Agarwal, 2003). The most obvious symptom of osteoporosis in the internal structure of long bones is a complex alteration of the trabecular patterns in the metaphyses and epiphyses and a tendency towards fracture, particularly in the femoral neck.…”

Section: Introductionmentioning

confidence: 99%

“…The most obvious symptom of osteoporosis in the internal structure of long bones is a complex alteration of the trabecular patterns in the metaphyses and epiphyses and a tendency towards fracture, particularly in the femoral neck. As females are exposed to both Type I osteoporosis (menopausal) and Type II osteoporosis (senile; suffered by both males and females), they are at greater risk, at an earlier age, than males in all populations (Aufderheide & Rodriguez-Martin, 1998;Brickley & Agarwal, 2003;Schultz, 2003). The external manifestations of low BMC are initially less obvious.…”

Section: Introductionmentioning

confidence: 99%

Morphological changes in the shape of the non‐pathological bony knee joint with age: a morphometric analysis of the distal femur and proximal tibia in three populations of known age at death

Stevens

Viðarsdóttir

2007

Intl J of Osteoarchaeology

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This study examines possible morphological variation in the knee joint of Homo sapiens with increasing age in ostensively healthy and non-pathological distal femora and proximal tibiae. Throughout the lifetime of each individual, the hard tissue of the knee undergoes considerable remodelling as a response to biomechanical stresses, changes in bone microarchitecture and reduction of bone mineral content as a concomitant of ageing. The knee is also subject to greater levels of degenerative joint disease than any other joint. If death occurs whilst such diseases are in the earliest stages, initial bone changes may not be visually obvious in museum specimens. If such specimens are used for comparative analyses, it is hypothesised that changes might render it problematic if all ages are conglomerated into discrete samples. This study therefore investigates the degree to which the distal femur and proximal tibia change shape during ageing and, if changes are present, whether they are expressed similarly in males and females. It also examines whether changes are of greater magnitude than those morphological differences which might exist between populations. In an example population of African-Americans, results indicate that there is a statistically significant difference in shape between age groups and those differences become progressively greater between the youngest and oldest adults. Results also show that although morphological variation caused by ageing is apparent, those shape differences attributable to sexual dimorphism are more powerful. When two additional populations are analysed jointly with the African-Americans (Caucasian Americans and the European Spitalfields sample), results indicate that inter-population shape differences are considerably greater than differences caused by increasing age. Results imply that it is justifiable to combine specimens of all ages into discrete samples for comparative purposes.

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“…Measures of bone mass are often used as an indicator of skeletal health and lifetime skeletal dynamics (Brickley and Agarwal, 2003). Although measures of bone mass are presented as an accurate representation of overall skeletal health, they are often derived from only one or two skeletal elements.…”

mentioning

confidence: 99%

Intraskeletal variability in bone mass

Peck

Stout

2006

American J Phys Anthropol

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For methodological or other reasons, a variety of skeletal elements are analyzed and subsequently used as a basis for describing general bone loss and mass. However, bone loss and mass may not be uniform within and among skeletal elements of the same individual because of biomechanical factors. We test the hypothesis that a homogeneity in bone mass exists among skeletal elements of the same individual. Measures indicative of bone mass were calculated from the midshafts of six skeletal elements from the same individuals (N = 41). The extent of intraskeletal variability in bone mass (relative cortical area) was then examined for the entire sample, according to age, sex, and pathological status. The results of the analysis showed that all measures reflect a heterogeneity in bone mass (P

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Techniques for the Investigation of Age-Related Bone Loss and Osteoporosis in Archaeological Bone

Cited by 20 publications

References 73 publications

Metacarpal radiogrammetry: a useful indicator of bone loss throughout the skeleton?

Metacarpal radiogrammetry: a useful indicator of bone loss throughout the skeleton?

Morphological changes in the shape of the non‐pathological bony knee joint with age: a morphometric analysis of the distal femur and proximal tibia in three populations of known age at death

Intraskeletal variability in bone mass

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