Technical Note: Multipurpose CT, ultrasound, and MRI breast phantom for use in radiotherapy and minimally invasive interventions

Ruschin, Mark; Davidson, Sean M.; Phounsy, William; Yoo, Tae Sun; Chin, Lee; Pignol, Jean-Philippe; Ravi, Ananth; McCann, Claire

doi:10.1118/1.4947124

Cited by 25 publications

(31 citation statements)

References 30 publications

(36 reference statements)

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“…Previously reported MR/CT-visible materials in the literature did not meet IROC-Houston's criteria since most of these materials shared short shelf lives and required refrigeration storage. [14][15][16] We tested over 80 materials, which could potentially be used to manufacture IROC-Houston's MRgRT TABLE III. A measured film PDD curve and a TPS PDD curve were generated for both current IROC-Houston's phantom materials and testing materials for a large (10 9 10 cm 2 ), medium (6 9 6 cm 2 ), and small (3 9 3 cm 2 ) field size.…”

Section: Discussionmentioning

confidence: 99%

“…Other researchers have attempted to create dual MR/CT phantoms, but the phantoms are limited by either: shelf-life storage, require refrigeration or additives to prevent microorganism growth and therefore were not suitable for shipping to other RT institutions. [14][15][16] The aim of this study was to identify and characterize synthetic tissue equivalent (STE) materials that could be used to develop an anthropomorphic dual MR/CT QA phantom which would require minimal maintenance, and be used to credential RT institutions wishing to use MRgRT modalities in NCI-funded clinical trials.…”

Section: Introductionmentioning

confidence: 99%

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Developing and characterizing MR/CT‐visible materials used in QA phantoms for MRgRT systems

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Developing and characterizing MR/CT‐visible materials used in QA phantoms for MRgRT systems

et al. 2017

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“…Biopolymers have a high mass fraction of water, and their features are analogous to those of soft tissues . Various phantoms are manufactured using polysaccharides, agar, agarose and gelatin . However, water evaporation and bacterial growth are the major limitations to the long‐term preservation of biopolymers, and phantoms constructed from these materials .…”

Section: Introductionmentioning

confidence: 99%

“…Various phantoms are manufactured using polysaccharides, agar, agarose and gelatin . However, water evaporation and bacterial growth are the major limitations to the long‐term preservation of biopolymers, and phantoms constructed from these materials . Chemically synthesized polymers are more stable and durable than biopolymers, but they show a certain degree of deviation from human tissues due to the lack of water …”

Section: Introductionmentioning

confidence: 99%

Characterizing mechanical and medical imaging properties of polyvinyl chloride‐based tissue‐mimicking materials

Qin

Dyer

et al. 2019

J Applied Clin Med Phys

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Polyvinyl chloride (PVC) is a commonly used tissue‐mimicking material (TMM) for phantom construction using 3D printing technology. PVC‐based TMMs consist of a mixture of PVC powder and dioctyl terephthalate as a softener. In order to allow the clinical use of a PVC‐based phantom use across CT and magnetic resonance imaging (MRI) imaging platforms, we evaluated the mechanical and physical imaging characteristics of ten PVC samples. The samples were made with different PVC‐softener ratios to optimize phantom bioequivalence with physiologic human tissue. Phantom imaging characteristics, including computed tomography (CT) number, MRI relaxation time, and mechanical properties (e.g., Poisson’s ratio and elastic modulus) were quantified. CT number varied over a range of approximately −10 to 110 HU. The relaxation times of the T1‐weighted and T2‐weighted images were 206.81 ± 17.50 and 20.22 ± 5.74 ms, respectively. Tensile testing was performed to evaluate mechanical properties on the three PVC samples that were closest to human tissue. The elastic moduli for these samples ranged 7.000–12.376 MPa, and Poisson’s ratios were 0.604–0.644. After physical and imaging characterization of the various PVC‐based phantoms, we successfully produced a bioequivalent phantom compatible with multimodal imaging platforms for machine calibration and image optimization/benchmarking. By combining PVC with 3D printing technologies, it is possible to construct imaging phantoms simulating human anatomies with tissue equivalency.

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“…Numerous low-cost DIY breast phantoms have been proposed. Turkey breast embedded with peas and gel-based phantoms are the most commonly used models in ultrasound-guided breast biopsy simulation training [12,[14][15][16][17][18][19][20][21][22][23]25]. Although turkey breast can be easily obtained from the supermarket, its preparation process, such as cleaning and thawing, can be troublesome and is not user friendly.…”

Section: Discussionmentioning

confidence: 99%

Low-cost and easily fabricated ultrasound-guided breast phantom for breast biopsy training

Kuo

Lin

2020

Preprint

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Background: We developed an inexpensive and easy-to-fabricate gelatin-based breast biopsy training phantom and evaluated its effectiveness in improving the biopsy skill level and confidence level of residents.Methods: Six residents were requested to evaluate the effectiveness of the double-layered breast phantom, which contained a malignant tumor, two benign tumors, and a cyst. The Young’s modulus and acoustic properties of the gelatin tissue phantom and simulated tumors were investigated.Results: The result showed that 83% (n=5) of the participants agreed that the ultrasound image quality produced by the breast phantom was excellent or good. However, only 17% (n=1) of the participants claimed that there was room of improvement for the haptic feedback they received during the placement of core needle into the breast phantom. The mean pre-instructional score was 17% (SD 33%) for all participants. The mean post-instructional score was 83% (SD 33%), giving an overall improvement of 1.32/2 mean scores. The mean needle biopsy skill and confidence levels of the participants substantially increased through simulation training on our breast phantom.Conclusions: The proposed breast phantom can be easily fabricated by a resident for breast biopsy training. Simulation training using our breast phantom can improve a resident's confidence when performing challenging ultrasound-guided breast biopsy. According to the participants’ feedback, our breast phantom is sufficiently realistic in terms of ultrasound imaging and haptic feedback during needle insertion; thus, the training outcome can be linked to the performance of residents when they perform a live biopsy.

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Technical Note: Multipurpose CT, ultrasound, and MRI breast phantom for use in radiotherapy and minimally invasive interventions

Cited by 25 publications

References 30 publications

Developing and characterizing MR/CT‐visible materials used in QA phantoms for MRgRT systems

Developing and characterizing MR/CT‐visible materials used in QA phantoms for MRgRT systems

Characterizing mechanical and medical imaging properties of polyvinyl chloride‐based tissue‐mimicking materials

Low-cost and easily fabricated ultrasound-guided breast phantom for breast biopsy training

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