Technical method. Fine needle aspiration cytology of the breast using the Cytospin method

Fine Needle Aspiration Biopsy of Breast Lesions and Histopathologic Correlation

“…That method bypasses the critical procedure of skilled direct smear preparation. [8][9][10] Those results are similar to those obtained in our series. Thus, our study showed that direct smear methods seem to be comparable to the Cytospin method for FNAB.…”

“…Our results were obtained on direct smears. A recent article 10 showed a sensitivity of 95.2%, specificity of 96.5% and positive predictive value for malignancy of 100% with smears prepared using the Cytospin method (Shandon, Runcorn, England). That method bypasses the critical procedure of skilled direct smear preparation.…”

“…1,13 It has high diagnostic accuracy. [1][2][3][4]6,7,10,11,14,16,18 Nonetheless, some wide variations, between 76% 21,23-26 and 95%, 4 have been reported.…”

Criteria for the Diagnosis of Fibroepithelial Lesions of the Breast with Liquid-Based Cytology

“…The sensitivity was 95.2% and the specificity 96.5%, excluding inadequate samples. 2 The Cytospin and ThinPrep methods of fine needle aspiration specimen preparation are convenient in an outpatient setting and obviate the need for skillful preparation of direct smears. 2 Based on this study, we think that fibroepithelial lesions of the breast can be accurately differentiated on ThinPrep samples.…”

Needle Biopsy Diagnosis of Breast Cancer

“…It may be convenient in an outpatient setting, in which one physician obtains the specimen and another interprets it. The Cytospin method of processing material aspirated from breasts is equal in sensitivity and specificity to skillful preparation of direct smears 16 ; however, it is more expensive and time-consuming. The aspirated material from either a solid mass or a cyst can also be expelled directly in Cytolyt solution (Cytyc Corp., Marlborough, MA) for a Papanicolaou-stained monolayered cell preparation (ThinPrep, Cyte Corp., Marlborough, MA).…”