Technical description of endoscopic ultrasonography with fine-needle aspiration for the staging of lung cancer

Kramer, Henk; Putten, John W. G. van; Douma, W. Rob; Smidt, Alie A.; Dullemen, Hendrik M. van; Groen, Harry J.M.

doi:10.1016/j.rmed.2004.06.011

Cited by 14 publications

(7 citation statements)

References 23 publications

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“…Stations 8 and 9 can only be sampled by EUS, also, station 5 is easier to sample by EUS than by EBUS (14,15). Besides this, the easily sampled stations 2R and 4R by EBUS-TBNA can be seen with EUS; however sampling these stations is sometimes difficult because of their distant location (16,17). In a recent trial analyzing false negative results by EBUS-TBNA, EUS-FNA and combined procedure, the investigators found the false negative results of 23.8%, 28.6% and 14.7% per nodal station basis, respectively (18).…”

Section: Discussionmentioning

confidence: 99%

The role of endobronchial and endoscopic ultrasound guided fine needle aspiration for mediastinal nodal staging of non-small-cell lung cancer

et al. 2018

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The role of endobronchial and endoscopic ultrasound guided fine needle aspiration for mediastinal nodal staging of non-smallcell lung cancer Introduction: Mediastinal and hilar nodal staging is one of the key points for differentiating treatment modalities in patients with nonsmall-cell lung cancer (NSCLC). The aim of the present study was to determinate the diagnostic yields of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and combined EBUS-TBNA and EUS-FNA modalities for nodal staging in potentially operable NSCLC patients. Materials and Methods: Twenty consecutive patients were prospectively enrolled in the study between March 2014 and November 2015. All patients had a potentially operable NSCLC diagnosis before endosonographic procedures.

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Section: Discussionmentioning

confidence: 99%

The role of endobronchial and endoscopic ultrasound guided fine needle aspiration for mediastinal nodal staging of non-small-cell lung cancer

et al. 2018

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“…After the patient was sedated using a combination of midazolam and pentazocine, the echoendoscope was advanced to the stomach, and the left adrenal gland, celiac region and left lobe of the liver were observed. The echoendoscope was then gradually withdrawn to the esophagus, and the following regions were evaluated: pulmonary ligament, paraesophageal, subcarinal, lower paratracheal, subaortic and upper paratracheal [25]. After the initial orientation, LNs larger than 5 mm across the short axis were intended for FNA.…”

Section: Methodsmentioning

confidence: 99%

Mediastinal Lymph Node Staging in Potentially Resectable Non-Small Cell Lung Cancer: A Prospective Comparison of CT and EUS/EUS-FNA

et al. 2009

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Background: Mediastinal lymph node staging (N-staging) is essential to optimize the treatment in non-small cell lung cancer (NSCLC). Transesophageal endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) has recently been introduced as a complementary method. However, in most reports, EUS-FNA has been performed in patients who have demonstrated enlarged lymph nodes (LNs) on CT findings. The yield of EUS/EUS-FNA in patients without enlarged mediastinal LNs by CT has so far only been evaluated in a few reports. Aims: Our aim was to compare the diagnostic accuracy of CT and EUS with or without EUS-FNA (EUS/EUS-FNA) prospectively, for N-stage in all patients with potentially resectable NSCLC, including patients with and without mediastinal LN enlargement based on CT findings. Methods: Eighty consecutive patients with potentially resectable NSCLC based on CT findings were enrolled in this prospective comparative study, and underwent EUS/EUS-FNA. Results: Pathological N-stage was established in 78 patients, while in another 2 cases, malignant pleural effusion was proven by EUS-FNA, and we avoided further N-staging. In the 78 patients, the prevalence of malignant mediastinal LNs was 21%. The accuracy of EUS/EUS-FNA (91%) was significantly higher than that of CT (71%). The negative predictive value of EUS/EUS-FNA was 90%. In addition, EUS-FNA identified 2 patients as N3 disease in 56 patients without mediastinal LN involvement on CT. Conclusions: EUS/EUS-FNA gave more accurate N-staging in patients with possibly resectable NSCLC than CT, and is thus considered to be useful to determine the optimal treatment strategy.

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“…EUS-FNA was performed in an out-patient setting under local anesthesia (with or without moderate sedation) using the curved linear scanning ultrasound endoscope (GF-UCT160-OL5; Olympus, Aartselaar, Belgium) connected to the ultrasound unit (Aloka, Mechelen, Belgium) (10), with monitoring of heart rate and oxygen saturation (16). Punctures were performed with a 22-gauge fine needle (EUS-needle; Olympus).…”

Section: Eus-fnamentioning

confidence: 99%

Endoscopic Ultrasound Reduces Surgical Mediastinal Staging in Lung Cancer

Tournoy¹,

Ryck²,

Vanwalleghem³

et al. 2008

Am J Respir Crit Care Med

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Technical description of endoscopic ultrasonography with fine-needle aspiration for the staging of lung cancer

Abstract: EUS-FNA is minimally invasive, accurate, and fast. Anatomical areas can be reached that are inaccessible for cervical mediastinoscopy. EUS-FNA is useful for the staging of lung cancer or the assessment and diagnosis of abnormalities in the posterior mediastinum.

Cited by 14 publications

References 23 publications

The role of endobronchial and endoscopic ultrasound guided fine needle aspiration for mediastinal nodal staging of non-small-cell lung cancer

The role of endobronchial and endoscopic ultrasound guided fine needle aspiration for mediastinal nodal staging of non-small-cell lung cancer

Mediastinal Lymph Node Staging in Potentially Resectable Non-Small Cell Lung Cancer: A Prospective Comparison of CT and EUS/EUS-FNA

Endoscopic Ultrasound Reduces Surgical Mediastinal Staging in Lung Cancer

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