Abstract:Significance: Photoacoustic imaging (PAI) is an emerging functional and molecular imaging technology that has attracted much attention in the past decade. Recently, many researchers have used the Vantage Verasonics® research system for simultaneous ultrasound (US) and photoacoustic (PA) imaging. This was the motivation to write on the details of US/PA imaging system implementation and characterization using Verasonics platform.
Aim:We describe the subtle details of US/PA imaging system setup, study the perform… Show more
“…In addition, specificity of unmixing algorithms require improvements [38] , [40] , [49] , which goes hand-in-hand with further standardization and improvement of OAI systems [50] . This, together with improved analysis and reconstruction techniques using artificial intelligence, could improve the quality of the data [51] .…”
“…In addition, specificity of unmixing algorithms require improvements [38] , [40] , [49] , which goes hand-in-hand with further standardization and improvement of OAI systems [50] . This, together with improved analysis and reconstruction techniques using artificial intelligence, could improve the quality of the data [51] .…”
“…Imaging deeper structures in the tissue require more data to be acquired per point, thus needs more time to compress. Photoacoustic computed tomography (PACT) can image deeper structures and has approximately 1000 times lower pulse repetition rate (10-100 Hz), giving ~1000 times more time for compression per acquisition [10,11]. Therefore, our developed compression algorithms can comfortably be utilized in PACT system applications as well.…”
Photoacoustic microscopic images can assist specialists in disease diagnosis by providing vascular information. However, the size of such data is usually extremely large (ie, gigabytes), and thus, a real-time, efficient compression method can facilitate easy storage and transportation of these images. We have implemented multiple data compression methods in LabVIEW with a high compression ratio and execution times below the repetition rate of the pulsed laser. The qualitative and quantitative results of ex vivo and in vivo imaging with compression showed near-identical images to uncompressed images, with significantly smaller size.
“…The PA signals were acquired with a Vantage 128 ultrasound research system (Verasonics, Redmond, WA). The PACT imaging system had an axial resolution of 200 µm and a lateral resolution of 400 µm within 2 cm imaging depth [46] . Fig.…”
The investigation of neuronal activity in non-human primate models is of critical importance due to their genetic similarity to human brains. In this study, we tested the feasibility of using photoacoustic imaging for the detection of cortical and subcortical responses due to peripheral electrical stimulation in a squirrel monkey model. Photoacoustic computed tomography and photoacoustic microscopy were applied on squirrel monkeys for real-time deep subcortical imaging and optical-resolution cortical imaging, respectively. The electrically evoked hemodynamic changes in primary somatosensory cortex, premotor cortices, primary motor cortex, and underlying subcortical areas were measured. Hemodynamic responses were observed in both cortical and subcortical brain areas at the cortices during external stimulation, demonstrating the feasibility of photoacoustic technique for functional imaging of non-human primate brain.
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