Technical advances for abdominal wall closure after intestinal and multivisceral transplantation

Gerlach, Undine; Pascher, Andreas

doi:10.1097/mot.0b013e3283534d7b

Cited by 47 publications

(67 citation statements)

References 27 publications

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“…Although mesh-related infection is not usually life-threatening, its occurrence leads to posttransplant reintervention, use of indwelling catheters for longer periods of time and prolongation of hospital stay. To avoid this problem, several solutions for abdominal wall closure have been proposed such as graft size reduction; abdominal wall transplantation; or use of immunologically inert, acellular dermal matrix patches, which are less prone to infection (18).…”

Section: Discussionmentioning

confidence: 99%

Infectious Complications Following Small Bowel Transplantation

Silva

Juan

Fernández-Caamaño

et al. 2016

American Journal of Transplantation

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Microbiological spectrum and outcome of infectious complications following small bowel transplantation (SBT) have not been thoroughly characterized. We performed a retrospective analysis of all patients undergoing SBT from 2004 to 2013 in Spain. Sixty-nine patients underwent a total of 87 SBT procedures (65 pediatric, 22 adult). The median follow-up was 867 days. Overall, 81 transplant patients (93.1%) developed 263 episodes of infection (incidence rate: 2.81 episodes per 1000 transplant-days), with no significant differences between adult and pediatric populations. Most infections were bacterial (47.5%). Despite universal prophylaxis, 22 transplant patients (25.3%) developed cytomegalovirus disease, mainly in the form of enteritis. Specifically, 54 episodes of opportunistic infection (OI) occurred in 35 transplant patients. Infection was the major cause of mortality (17 of

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Section: Discussionmentioning

confidence: 99%

Infectious Complications Following Small Bowel Transplantation

Silva

Juan

Fernández-Caamaño

et al. 2016

American Journal of Transplantation

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“…NCCT stratification would spare only the 11–30% defined as low risk from angiographic imaging but yield a 1.6–8%% false negative rate [2], [24], [26]. An external validation of attempts to combine NCCT risk stratification with clinical variables including age, gender, hypertensive/anticoagulation status to define ‘low risk’ [1], [2], [7], [9], [24], [26] yielded an AUCs of 0.82 for predicting underlying vascular lesion presence with NCCT stratification faring as well as a combined imaging/radiological score [27]. The average performance of NCCT therefore provides a compelling argument for consideration of a CTA base screening algorithm given its sensitivity and specificity ranging from 92–100% for secondary vascular lesion detection [2]–[5], [7]…”

Section: Discussionmentioning

confidence: 98%

The Cost-Utility of CT Angiography and Conventional Angiography for People Presenting with Intracerebral Hemorrhage

et al. 2014

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ObjectiveTo determine the optimal imaging strategy for ICH incorporating CTA or DSA with and without a NCCT risk stratification algorithm.MethodsA Markov model included costs, outcomes, prevalence of a vascular lesion, and the sensitivity and specificity of a risk stratification algorithm from the literature. The four imaging strategies were: (a) CTA screening of the entire cohort; (b) CTA only in those where NCCT suggested a high or indeterminate likelihood of a lesion; (c) DSA screening of the entire cohort and (d) DSA only for those with a high or indeterminate suspicion of a lesion following NCCT. Branch d was the comparator.ResultsAge of the cohort and the probability of an underlying lesion influenced the choice of optimal imaging strategy. With a low suspicion for a lesion (<12%), branch (a) was the optimal strategy for a willingness-to-pay of $100,000/QALY. Branch (a) remained the optimal strategy in younger people (<35 years) with a risk below 15%. If the probability of a lesion was >15%, branch (b) became preferred strategy. The probabilistic sensitivity analysis showed that branch (b) was the optimal choice 70–72% of the time over varying willingness-to-pay values.ConclusionsCTA has a clear role in the evaluation of people presenting with ICH, though the choice of CTA everyone or CTA using risk stratification depends on age and likelihood of finding a lesion.

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“…Abdominal wall with solid organs Multivisceral or intestinal transplant recipients often suffer loss of AWD secondary to multiple abdominal operations [28]. Loss of AWD is a morbid condition and afflicts a wide variety of patients [28,29].…”

Section: Upper Extremity With Solid Organsmentioning

confidence: 99%

Procurement strategies for combined multiorgan and composite tissues for transplantation

Datta¹,

Yersiz²,

Kaldas³

et al. 2015

Current Opinion in Organ Transplantation

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Technical advances for abdominal wall closure after intestinal and multivisceral transplantation

Abstract: Abdominal wall reconstruction after ITX/MVTX is commonly demanded and can be conducted by different strategies. The technique should be easy to use in a timely manner and should prevent abdominal infections, intestinal fistulation, incisional hernias, and wound dehiscence.

Cited by 47 publications

References 27 publications

Infectious Complications Following Small Bowel Transplantation

Infectious Complications Following Small Bowel Transplantation

The Cost-Utility of CT Angiography and Conventional Angiography for People Presenting with Intracerebral Hemorrhage

Procurement strategies for combined multiorgan and composite tissues for transplantation

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