Tear film function and corneal sensation in the early postoperative period after LASEK for the correction of myopia

Abstract

LASEK alters ocular surface haemostasis and reduces corneal sensation in the early postoperative period. Subjective symptoms of dry eye were described during the first 2 months after surgery.

Comparison of dry-eye disease severity after laser in situ keratomileusis and laser-assisted subepithelial keratectomy

“…2 In our study, the OSDI scores remained unchanged from baseline to 3 months, 6 months, and 12 months. The postoperative change in OSDI was significantly higher in LASIK patients than in LASEK patients at 3 months, suggesting that LASIK patients had a greater increase in the level of dry-eye symptoms than LASEK patients.…”

“…The levels of topical lubricant use in our study are comparable with the incidence of dry-eye disease reported in other studies. 2,5,6 For example, in another study, 5 dry-eye disease after LASIK affected approximately 50% of patients at 1 week, 40% at 1 month, and 20% to 40% at 6 months.…”

“…5 Laser-assisted subepithelial keratectomy (LASEK) is also associated with transient postoperative dry-eye symptoms. 2,6 Lemp et al 7 report tear osmolarity as a new reliable metric for diagnosis and classification of dry-eye disease. Versura et al 8 found that the measured tear osmolarity had a 98.4% positive predictive value for diagnosing dry eye, conferring a likelihood ratio of 10.99.…”

“…Dry-eye disease or tear dysfunction is the most common source of morbidity after refractive laser procedures, [1][2][3][4] affecting approximately 50% of laser in situ keratomileusis (LASIK) (120 mm flap) patients at 1 week, 40% at 1 month, and 20% to 40% at 6 months.…”

Clinical Effectiveness of Topical Cyclosporine A 0.05% After Laser Epithelial Keratomileusis

“…28 After LASEK, ocular irritation symptoms developed, and tear film BUT and Schirmer test values were reduced in the early postoperative period. 29 Conventional treatment for postrefractive surgery dry eye includes artificial tears, punctal plug, and serum eye drops. 30 Several studies have reported the effectiveness of cyclosporine A 0.05% eye drops in LASIK procedures.…”