Teaching Poetry: An Exercise in Practical Criticism

Hartman, Joan E.

doi:10.2307/375193

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Characterization Of Suc1 Transcripts1

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1986

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“…The sucl mutants could be suppressing cdc2 mutants by opening up a pathway which bypasses the requirements for the cdc2 gene function (Hartman and Roth, 1973). If this were so then the various sucl mutants would allow all cdc2ts mutants to grow at the restrictive temperature.…”

Section: Characterization Of Suc1 Transcriptsmentioning

confidence: 99%

suc1 is an essential gene involved in both the cell cycle and growth in fission yeast

1986

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The gene suc1 encodes a product which suppresses certain temperature sensitive mutants of the cell cycle control gene cdc2 of Schizosaccharomyces pombe. Mutants in the suc1 gene or over‐expression of its product leads to delays in mitotic and meiotic nuclear division. Deletion of the suc1 gene is lethal and generates some cells blocked in the cell cycle and others impaired in cellular growth. It is likely that the suc1 gene product binds and forms unstable complexes with the cdc2 protein kinase and with other proteins necessary for the cell cycle and cellular growth. suc1 may have a regulatory role in these processes.

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Section: Characterization Of Suc1 Transcriptsmentioning

confidence: 99%