Teaching a biology laboratory course using Dictyostelium

Knecht, David A.; Cooper, Kate; Moore, Jonathan E.

doi:10.1387/ijdb.190249dk

Cited by 3 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dictyostelium belongs to the amoebozoa group, and although this group of organisms diverged before the opistokonta (fungi and animals), it retains many features of animal cells that have been lost during the evolution of fungi. Cell motility and chemotaxis, phagocytosis and macropynocytosis are very similar to those observed in animal cells and Dictyostelium presents a multicellular stage that allows the study of cell differentiation and morphogenesis (see this series of reviews collected in a special issue dedicated to Dictyostelium in IJDB ( Araki and Saito, 2019 ; Batsios et al, 2019 ; Bloomfield, 2019 ; Bozzaro, 2019 ; Consalvo et al, 2019 ; Escalante and Cardenal-Muñoz, 2019 ; Farinholt et al, 2019 ; Fey et al, 2019 ; Fischer and Eichinger, 2019 ; Ishikawa-Ankerhold and Müller-Taubenberger, 2019 ; Jaiswal et al, 2019 ; Kawabe et al, 2019 ; Kay et al, 2019 ; Knecht et al, 2019 ; Kundert and Shaulsky, 2019 ; Kuspa and Shaulsky, 2019 ; Medina et al, 2019 ; Nanjundiah, 2019 ; Pal et al, 2019 ; Pearce et al, 2019 ; Pergolizzi et al, 2019 ; Schaf et al, 2019 ; Vines and King, 2019 ). Individual Dictyostelium cells ingest bacteria and yeasts in soil and the transition to a multicellular state, triggered when the food source is depleted, is accomplished by aggregation of preexisting cells.…”

Section: The Yeast and Dictyostelium Models In Autophagy And Diseasementioning

confidence: 90%

The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models

Vincent

Antón-Esteban

Bueno-Arribas

et al. 2021

Front. Cell Dev. Biol.

View full text Add to dashboard Cite

WIPIs are a conserved family of proteins with a characteristic 7-bladed β-propeller structure. They play a prominent role in autophagy, but also in other membrane trafficking processes. Mutations in human WIPI4 cause several neurodegenerative diseases. One of them is BPAN, a rare disease characterized by developmental delay, motor disorders, and seizures. Autophagy dysfunction is thought to play an important role in this disease but the precise pathological consequences of the mutations are not well established. The use of simple models such as the yeast Saccharomyces cerevisiae and the social amoeba Dictyostelium discoideum provides valuable information on the molecular and cellular function of these proteins, but also sheds light on possible pathways that may be relevant in the search for potential therapies. Here, we review the function of WIPIs as well as disease-causing mutations with a special focus on the information provided by these simple models.

show abstract

Section: The Yeast and Dictyostelium Models In Autophagy And Diseasementioning

confidence: 90%

The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models

Vincent

Antón-Esteban

Bueno-Arribas

et al. 2021

Front. Cell Dev. Biol.

View full text Add to dashboard Cite

show abstract

Glimpses of Dictyostelid research in India

Begum¹,

Saran²

2020

Int. J. Dev. Biol.

View full text Add to dashboard Cite

Simple organisms are preferred for understanding the molecular and cellular function(s) of complex processes. Dictyostelium discoideum is a lower eukaryote, a protist and a cellular slime mould, which has been in recent times used for various studies such as cell differentiation, development, cell death, stress responses etc. It is a soil amoeba (unicellular) that undertakes a remarkable, facultative shift to multicellularity when exposed to starvation and requires signal pathways that result in alteration of gene expression and finally show cell differentiation. The amoebae aggregate, differentiate and form fruiting bodies with two terminally differentiated cells: the dead stalk (non-viable) and dormant spores (viable). In India, starting from the isolation of Dictyostelium species to morphogenesis, cell signalling and social evolution has been studied with many more new research additions. Advances in molecular genetics make Dictyostelium an attractive model system to study cell biology, biochemistry, signal transduction and many more.

show abstract

On improving the professional training of future biology teachers

Gaissina,

Childibaev,

Tatarinova

et al. 2023

Scientific Herald of Uzhhorod University Series Physics

View full text Add to dashboard Cite

Relevance. Higher education is designed to transfer to the student the knowledge, skills, and abilities in a particular field, promote the formation of humanistic values, broaden the student’s horizons, develop his/her ability to make creative solutions, and practice self-study. Professional training of future biology teachers shifts the focus to upbringing, developmental functions of education, the formation of a future teacher's personality, his/her holistic spiritual and moral development, high psychological stability, and readiness for the profession. Purpose. The study aimed to develop and substantiate the professional training of future teachers when studying pedagogical, methodological, and natural disciplines in pedagogical universities to promote the development of cognitive and professional interest of graduates, the formation of deep and persisting knowledge, and activate their professional self-determination. Methodology. We have identified the main directions for the formation of professional qualities of students in the upbringing and training process and during production practice (visits to the best schools; conducting lectures, practical and laboratory classes with the elements of profiling; the use of professional literature, elective courses, etc.). Results. Professional training of future biology teachers allows the subject of activity to reach the level that is legally required and sufficient for pedagogical activity. Conclusions. A 21st-century teacher should possess the following qualities: reflectivity in thinking and practical activity; tolerance; affection, love, tenderness; interest in technology and digital information; global awareness.

show abstract

Teaching a biology laboratory course using Dictyostelium

Cited by 3 publications

References 7 publications

The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models

The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models

Glimpses of Dictyostelid research in India

On improving the professional training of future biology teachers

Contact Info

Product

Resources

About