Due to the recent outbreak of the COVID-19 pandemic, the institutions of higher education had to transform their educational function from face-to-face to e-learning. The purpose of this study is to examine the effects of e-learning and the consequent disruption of the traditional educational function in higher education in Greece with special reference to the views of undergraduates compared to those of their peers collected via the same method and tool one year earlier in two regional Greek Universities, the University of Patras and the Democritus University of Thrace. The present research was conducted in May 2021 in order to explore students’ views and feelings one year after the sudden and total transition to online teaching during the pandemic. The results suggest that students seem to prefer face-to-face courses, but they provide interesting aspects regarding e-teaching and learning -thus valuable guidelines for higher educational institutions in developing didactic approaches, to motivate students on their academic pathway, emphasizing the necessity of University Pedagogy.