Background: This article aims to provide currently available data and insight science knowledge on association between teas, their polyphenols and the risk of cancers including prostate, liver, lung, gastric, breast, colon and colorectal, esophageal, oral cavity, non-hodgkin's lymphoma, esdometrial, and pancreatic based on published studies by searching Pub Med and database of Web of Science belonging Institute for Science Information and secondary referencing qualified for inclusion. In addition, the molecular mechanisms of tea in cancer prevention also briefly discussed. The authors hope that this work will be help for readers, researches, reviewers, and editors who are interested in the related field of the Camellia sinensis tea studies.