TCT-441 Traditional and genetic risk factors in young patients with myocardial infarction in Iraq

Mohammad, Ameen Mosa; Othman, Galawezh; Saeed, Chiman Hameed; Allawi, Nasir

doi:10.1016/j.jacc.2017.09.548

Cited by 2 publications

(2 citation statements)

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“…24 Generally, the traditional cardiovascular risk factors are clustering with the increasing incidence among Iraqi patients with CAD. 25 The management strategy applied in the current study showed that about 70% of cases were managed by an invasive interventional approach, and 30% were managed conservatively. However, the medical guidelines recommend a routine invasive strategy for almost all patients with NSTEMI within a limited time to improve the composite ischemic outcomes.…”

Section: Discussionmentioning

confidence: 72%

Clinico-angiographic profiles and in-hospital outcomes of non-ST segment elevation myocardial infarction in Kurdistan Region of Iraq

Mohammad

Issa

Saeed

2022

J. Contemp. Med. Sci.

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Objectives: This work aimed to study the clinical, angiographic profiles and in-hospital outcomes of NSTEMI cases in Duhok, Iraq. Methods: This prospective study involved 283 patients with NSTEMI who were admitted to Azadi teaching hospital/Azadi heart center in Duhok, Kurdistan region of Iraq, between 2021 and 2022. The patient's demographic variables, major cardiovascular risk factors (smoking, hypertension, diabetes mellitus, hyperlipidemia and family history of coronary artery disease), clinical presentation, past history of myocardial infarction/ previous percutaneous coronary intervention (PCI) and drug history were collected. The GRACE risk score was calculated for each patient. Patients were followed up regarding the management strategies (whether conservative or invasive approach), and in-hospital complications and outcomes. Results: The mean GRACE score was 142±26. 70% of cases underwent coronary angiography/ angioplasty, with a mean time to the coronary intervention of 8 days. 17% of the sample had developed different cardiovascular complications, with heart failure being the most common. The mortality rate was 7.4%. Conclusion: The study demonstrated higher complications and mortality rates, especially among patients with higher GRACE scores, compared to rates found in most available studies, particularly in western countries. This finding could be secondary to a suboptimal coronary intervention for NSTEMI in terms of time to intervention and the proportion of patients who underwent it.

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Section: Discussionmentioning

confidence: 72%

Clinico-angiographic profiles and in-hospital outcomes of non-ST segment elevation myocardial infarction in Kurdistan Region of Iraq

Mohammad

Issa

Saeed

2022

J. Contemp. Med. Sci.

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“…7,8 The underlying mechanism of CAD tends to be complex and multifactorial, with the additive association of non-traditional risk factors to atherosclerosis. 9,10 Rheumatoid factor, anti-cyclic citrullinated peptide antibody, long duration of RA, and thrombogenic factors are among the non-traditional risk factors contributing to morbidity and mortality of CAD in RA [9][10][11][12] Given the fact that RA patients are less likely to experience symptoms of CAD and somewhat likely to develop unrecognized events and unforeseen death, the clinical presentation of CAD in such patients is different, apparently earlier, silent, and sudden. 13,14 RA patients were twice as likely to experience sudden death than non-RA subjects.…”

Section: Introductionmentioning

confidence: 99%

Silent Coronary Artery Disease in Patients with Rheumatoid Arthritis in Kurdistan, Iraq: A cross-sectional study

Mohammad

Mohammed

Rasul

et al. 2023

J. Contemp. Med. Sci.

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Objectives: This study attempts to determine the silent coronary artery disease (CAD) in a sample of Iraqi Kurdish patients diagnosed with rheumatoid arthritis (RA). Methods: A total of 50 such patients from Duhok, Kurdistan region of Iraq, underwent multi slices computed tomography (MSCT) coronary angiography 64 slices to determine coronary artery calcium (CAC) scores and coronary stenoses. Results: 62% of cases had a (CAC) score > zero on non-contrast MSCT scans. Coronary angiograms showed that 26 (52%) of the cases had variable coronary artery stenosis; 17(34%) of them were obstructive (>50% luminal narrowing). The study demonstrated that Inflammatory markers (rheumatoid factor, Anti- cyclic citrullinated peptides, and some cardiovascular risk factors, namely (hypertension and type 2 diabetes mellitus) were significantly related to the presence of CAD in these patients. Conclusions: Patients with rheumatoid arthritis are at increased risk of CAD. This risk is higher in the presence of inflammatory and cardiovascular risk factors.

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TCT-441 Traditional and genetic risk factors in young patients with myocardial infarction in Iraq

Cited by 2 publications

References 0 publications

Clinico-angiographic profiles and in-hospital outcomes of non-ST segment elevation myocardial infarction in Kurdistan Region of Iraq

Clinico-angiographic profiles and in-hospital outcomes of non-ST segment elevation myocardial infarction in Kurdistan Region of Iraq

Silent Coronary Artery Disease in Patients with Rheumatoid Arthritis in Kurdistan, Iraq: A cross-sectional study

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