“…Five studies assessed the impact of digital twins on virtual patients 15,16,[18][19][20] , while seven examined their effect on real-world patients 13,14,17,[21][22][23][24] . These patients included had various diseases, including cancer (4/12, 33.33%) 15,16,19,22 , type 2 diabetes (2/12, 16.66%) 13,14 , multiple sclerosis (2/12, 16.66%) 17,18 , qi deficiency (1/12, 8.33%) 21 , heart failure (1/12, 8.33%) 20 , post-hepatectomy liver failure (1/12, 8.33%) 23 , and dental issues (1/12, 8.33%) 24 . This review coded interventions into three types: personalized health management (3/12, 25.00%) 13,14,21 , precision individual therapy effects (3/12, 25.00%) 15,16,[18][19][20]22 , and predicting individual risk (3/12, 25.00%) 17,23,24 , with a total of 45 measured outcomes.…”