TBHP Promotes Cross-Dehydrogenative Coupling of SF4 Alkynes with Tetrahydroisoquinolines under Copper Catalysis
Srikanth Reddy Narra,
Putri Nur Arina Mohd Ariff,
Debarshi Saha
et al.
Abstract:We present a viable approach for the crossdehydrogenative coupling of Het-SF 4 -alkynes with tetrahydroisoquinolines under oxidative conditions, using TBHP and copper catalysts. These newly developed conditions boast enhanced yields and a more extensive range of substrates, demonstrating tolerance to various functional groups and addressing the limitations of earlier reports. Consequently, this method should increase opportunities for the exploration of SF 4 -containing compounds and their potential applicatio… Show more
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