Taxonomy of Pathogen Codetection in Pediatric Case Fatalities with Adenoviral Respiratory Infection

Abstract

Objective The aim of this study was to determine the prevalence and taxonomy of pathogen codetection in pediatric case fatalities associated with adenoviral respiratory infection. Methods This retrospective case series included 107 pediatric case fatalities associated with adenoviral respiratory infection. Results We observed a high rate of pathogen codetection with broad diversity from both respiratory and nonrespiratory sources. We noted differences in codetection characteristics based on immune status; most notably that immunocompromised cases were more likely to have bacteremia and adenoviremia. Conclusions In pediatric case fatalities associated with adenoviral respiratory infection, we observed a high degree of pathogen codetection.