Taxonomy and History

Martin, Brent J.

doi:10.1016/b978-0-12-380920-9.00038-9

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…There are the long-tailed chinchilla, Chinchilla lanigera, and the short-tailed chinchilla, Chinchilla chinchilla. Chinchillas originate from the Andes Mountains of South America (Martin et al, 2012). They are 400e800 g in size, females weighing more than males, with compact bodies and long, strong hind limbs and dense fur coats (Alworth et al, 2012).…”

Section: Chinchillasmentioning

confidence: 99%

Commonly Used Animal Models

Hickman

Johnson

Vemulapalli

et al. 2017

Principles of Animal Research

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Section: Chinchillasmentioning

confidence: 99%

Commonly Used Animal Models

Hickman

Johnson

Vemulapalli

et al. 2017

Principles of Animal Research

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“…As such, the requirements for laboratory husbandry of chinchillas are well established [ 8 ] along with standard operating procedures for basic experimental methods such as appropriate animal handling, body fluid sampling and compound administration [ 33 ], paving the way for the use of the chinchilla in other fields in biomedical research. There are no inbred strains or breeds of domestic chinchillas; however, three different varieties are recognized: la plata , costina and raton with small differences in musculature and limb length in addition to different colour variants such as grey, white, black and brown [ 34 ]. An important contribution to the chinchilla as a research model was made in 2012, when whole-genome shotgun sequencing of the chinchilla genome was completed, and the following year, when the sequencing of the mitochondrial genome was completed [ 35 ].…”

Section: Introductionmentioning

confidence: 99%

The chinchilla as a novel animal model of pregnancy

et al. 2017

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Several parameters are important when choosing the most appropriate animal to model human obstetrics, including gestation period, number of fetuses per gestation and placental structure. The domesticated long-tailed chinchilla (Chinchilla lanigera) is a well-suited and appropriate animal model of pregnancy that often will carry only one offspring and has a long gestation period of 105–115 days. Furthermore, the chinchilla placenta is of the haemomonochorial labyrinthine type and is therefore comparable to the human villous haemomonochorial placenta. This proof-of-concept study demonstrated the feasibility in laboratory settings, and demonstrated the potential of the pregnant chinchilla as an animal model for obstetric research and its potential usefulness for non-invasive measurements in the placenta. We demonstrate measurements of the placental and fetal metabolism (demonstrated in vivo by hyperpolarized MRI and in vitro by qPCR analyses), placental vessels (demonstrated ex vivo by contrast-enhanced CT angiography) and overall anatomy (demonstrated in vivo by whole-body CT).

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“…LABORATORY ANIMAL MEDICINE (Martin, 2012a). Today, chinchillas are successfully bred in captivity for their fur, for the pet trade, and for biomedical research.…”

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confidence: 99%