Taxol: Women with ovarian cancer participate in a new clinical trial

Brown, J R I; McDermott, Barbara; Runzer, Nancy

doi:10.5737/1181912x224750

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Case Reports Of Paclitaxel Extravasation1

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2003

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“…In a very early report, Brown and colleagues [12] briefly described two patients who experienced paclitaxel extravasation. These patients experienced slight swelling, erythema, and mild pain which resolved after 5-7 days.…”

Section: Case Reports Of Paclitaxel Extravasationmentioning

confidence: 99%

A review of clinical experience with paclitaxel extravasations

Stanford¹,

Hardwicke²

2003

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Paclitaxel is a novel antineoplastic with a wide spectrum of activity in various malignant tumors. Extravasation of chemotherapy drugs is a widely feared adverse event in oncology patients. A Medline search between 1966 and October 2002 was conducted to identify case reports related to paclitaxel extravasation, as well as a bibliography screening of identified papers. The goal of this work is to summarize the available reports of paclitaxel extravasation and assess its vesicant potential. Additionally, management strategies for extravasation events due to paclitaxel are assessed.

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Section: Case Reports Of Paclitaxel Extravasationmentioning

confidence: 99%