Taurolidine and Heparin as Catheter Lock Solution for Central Venous Catheters in Hemodialysis
Timothy Nguyen,
Bernard C. Camins,
David A. Butler
Abstract:Background:
Chronic kidney disease can lead to end-stage renal disease, and the prevalence is increasing. Many patients starting hemodialysis require central venous catheters (CVCs). Catheter-related bloodstream infections (CRBSIs) are a common complication and lead to significant morbidity and mortality. Interventions to prevent CRBSI include antimicrobial lock therapy but concern for the development of antimicrobial resistance and adverse effects. Nonantimicrobial antiseptics as catheter lock sol… Show more
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