Taurine supplementation improves liver glucose control in normal protein and malnourished mice fed a high‐fat diet

Abstract

Malnourished mice fed an HFD developed obesity, glucose intolerance, and increased liver glucose output. TAU preserved only normal liver glucose control in RHT mice, an effect associated with increased liver p-AMPK content.

Comparison between Fibroscan and Serum Taurine for Early Diagnosis of Liver Fibrosis in Egyptian Patients Infected with HCV

“…Taurine, 2-amino-ethanesulphonic acids, (Tau) an essential amino acid, present at high concentrations in the liver [17]. It has various physiological functions and protective properties including protection against various types of hepatic damage [18].…”

Taurine Supplementation Leads to a Disruption in Energy Homeostasis in Menopausal Obese Mice

“…4c ). Food intake in grams/week was converted into calories/ week for each group multiplying the value by 3.88 kcal/g for standard control (C) and 5.44 kcal/g for high fat diet (HFD) ( Batista et al 2013b ). Different letters over the bars denote signifi cant differences between groups ( P < 0.05).…”

“…Half of both C and H groups received drinking water supplemented with 3 % taurine (TAU) (CT or HT groups) until the end of the experiment. Diets were developed in accordance to AIN-93 guidelines for adult rodents and their nutritional composition was previously described (Reeves et al 1993 ;Batista et al 2013b ).…”

“…Studies have provided evidence for TAU as an important regulator of glucose homeostasis. For instance, supplementation of drinking water with TAU improves peripheral insulin sensitivity ( Batista et al 2013b ). Moreover, in vitro treatment with TAU has been shown to increase glucose and insulin tolerance as well as to increase calcium uptake by the islets of Langerhans (Ribeiro et al 2012a , b ).…”

Defects of the exchange of amino acids in the perinatal period

“…Материнське перинатальне харчування може програмувати метаболічні функції потомства; його порушення підвищує ризик метаболічного синдрому в зрілому віці [37]. Споживання їжі з високим вмістом ліпідів та сахарози може запро-грамувати ожиріння, вміст метильних донорів має вплив на регулювання циклу метіонін-гомо-цистеїн [38].…”