Tattoo removal with ingenol mebutate

Cozzi, Sarah-Jane; Le, Thuy T.; Ogbourne, Steven M.; James, Cini; Suhrbier, Andreas

doi:10.2147/ccid.s135716

Cited by 4 publications

(3 citation statements)

References 37 publications

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“…It activates protein kinase C which starts the inflammatory process resulting in necrosis and peeling of epidermis followed by crust formation which then falls off to initiate reepithelialization. 37,38 Like ingenol mebutate, imiquimod 5% has similar effects likeinducing inflammation in form of epidermal and dermal necrosis, neutrophil infiltration and eschar formation which helps in tattoos removal in a guinea pig studies. It induces production of TNFα and IFNγ thus activating innate and cell mediated immunity.…”

Section: Chemi C Al Tat Too Removalmentioning

confidence: 99%

“…Recently, 0.1% ingenol mebutate used for treating actinic keratoses has been helpful in tattoo removal as proven in animal studies. It activates protein kinase C which starts the inflammatory process resulting in necrosis and peeling of epidermis followed by crust formation which then falls off to initiate re‐epithelialization 37,38 . Like ingenol mebutate, imiquimod 5% has similar effects likeinducing inflammation in form of epidermal and dermal necrosis, neutrophil infiltration and eschar formation which helps in tattoos removal in a guinea pig studies.…”

Section: Chemical Tattoo Removalmentioning

confidence: 99%

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Non‐laser treatment for tattoo removal

Dash

Patil

Kassir

et al. 2022

J of Cosmetic Dermatology

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Tattoos are increasingly gathering attention in the young population, especially in second to fourth decade of life. With such trends, rate of its removal also has been on the rise. Treatment options for tattoo removal besides lasers are surgery, radiofrequency, infrared light, cryotherapy, dermabrasion and salabrasion. Unfortunately, none of these procedures are associated with satisfactory cosmetic results due to adverse effects such as scarring and dyspigmentation. Although laser treatment has become the gold standard for tattoo removal, it is also associated with some limitations. Some tattoo inks are resistant to laser, and multiple sessions and multiple wavelengths may be required for its complete removal. Considering these limitations, other treatment modalities for tattoo removal must be explored. This article highlights the non‐laser treatment options for tattoo removal. We reviewed all published literature identified from electronic databases (MEDLINE and PubMed) till August 2021 to highlight the non‐laser treatment options for tattoo removal.

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Section: Chemi C Al Tat Too Removalmentioning

confidence: 99%

Section: Chemical Tattoo Removalmentioning

confidence: 99%

Non‐laser treatment for tattoo removal

Dash

Patil

Kassir

et al. 2022

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…In humans, two randomised controlled trials of 5% imiquimod cream as an adjunct to laser therapy failed to show significant benefit and the combination with imiquimod was associated with a significantly higher risk of adverse events. [90] Ingenol mebutate is a US Food and Drug Administrationapproved topical treatment for actinic keratosis. Two applications of 0.1% ingenol mebutate gel consistently removed 2-week-old tattoos from hairless mice.…”

Section: Chemical Tattoo Removalmentioning

confidence: 99%

Tattoos: A summary knowledge for the practising clinician

2018

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Tattoos are not a symptom of a mental disturbance. Most of the tattooed have simple motives and explanations: 'because I like it', 'because I'm a tomboy', 'to remember'. They do not accept the interpretations that the researchers describe and impose. Actually, the act of tattooing is more sacred to the subjected than the tattoo itself. (Kazandjieva and Tsankov [1]) Tattoos are becoming increasingly common in all demographic groups globally and consequently so are clinician encounters with tattooed individuals. Tattoos have the potential to have an impact on clinicianpatient interaction, ultimately affecting clinical decision-making and patient outcomes. Tattoos may affect the clinician's first impression of the patient, their physical and psychological assessment, and thus their management of that patient. [2] Furthermore, tattoos and their complications are often the primary reason for seeking medical help. Considering the high prevalence of tattoos, many clinicians do not have sufficient knowledge of tattoos and tattooing to make informed clinical decisions. In this brief review, we provide practising clinicians with basic knowledge regarding tattoos to enable them to forge more functional clinician-patient relationships and to guide them in their daily practice. What is a tattoo? A tattoo refers to implantation of an exogenous pigment into the skin or mucous membranes. Types of tattoos Tattoos can be accidental or deliberate, permanent or temporary, professional or amateur, cosmetic, decorative or medical. Accidental tattoos are also referred to as traumatic tattoos, and result from inoculation into a wound of substances such as asphalt, amalgam, graphite, ink or gun powder. Permanent tattoos involve a colourfast pigment implanted below the dermo-epidermal junction and retained by macrophages and fibroblasts in the dermis. Temporary tattoos resemble a permanent tattoo, but are painted or airbrushed or are a decal on the surface of the skin and usually last for a few days. Professional tattoos are created by trained individuals at a tattoo parlour, usually with a tattoo machine. The pigment is mostly evenly dispersed in the dermis. Amateur tattoos are often applied at home, using only a needle and one colour ink. Ink deposition tends to be more superficial and variable. Cosmetic tattoos involve the use of pigment to enhance the appearance of body parts, resemble make-up or mask deformities. These include permanent make-up, tattoos over surgical scars and nipple tattoos after a mastectomy. Medical tattoos are used to treat a medical condition, communicate medical information, or mark a body location for medical procedures or future review. Invisible tattoos are also called UV or black-light tattoos and are made with dyes that fluoresce and glow visibly under ultraviolet light. History, evolution and epidemiology of tattoos Tattoos are as old as recorded human history, dating back >5 000 years. Ötzi the Iceman, whose 5 300-year-old freeze-dried body was discovered in the Tyrolean Alps in 1991, was tattooed over h...

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Tattoo Removal: Techniques and Devices

Cuyper¹

2018

Dermatologic Complications With Body Art

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Tattoo removal with ingenol mebutate

Cited by 4 publications

References 37 publications

Non‐laser treatment for tattoo removal

Non‐laser treatment for tattoo removal

Tattoos: A summary knowledge for the practising clinician

Tattoo Removal: Techniques and Devices

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