Abstract:Diagnosis of mental illness, testing of treatment effects, and design of prevention strategies all require brain-based biomarkers that can serve as effective targets of evaluation. The search for such markers often starts with a search for neural correlates from brain imaging studies with measures of functions and behavior of interest. Yet such an approach can produce erroneous results for correlations do not guarantee causation. Only when the markers map onto neurocomputationally-relevant parameters can such … Show more
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