“…These drawbacks affect to different biotechnological processes. More specifically, extremozymes (enzymes produced by extremophiles) have been the subject of a great interest, as their naturally developed resistance to harsh reaction conditions (chemical agents and extreme values of temperature, pH and salinity) makes them suitable for an array of biocatalytic reactions (Deive et al, 2012a In our group, we have bet in thermophiles, because working at elevated temperatures involves advantages such as reduced viscosities, higher reaction rates, lower resistance to mass transfer, lower risk of contamination and higher solubility of most of the substrates and products (Rothschild and Macinelli, 2001). In this sense lipases (EC 3.1.1.3) have been recognized among the topthree most interesting group of enzymes in terms of sales, with widespread use in industrial sectors as varied as food, drugs, biofuels and detergents, just to mention a few.…”