Abstract:Purpose: Recurrent and metastatic thyroid cancer is more invasive and can transform to dedifferentiated thyroid cancer, thus leading to a severe decline in the 10-year survival. The thyroid-stimulating hormone receptor (TSHR) plays an important role in differentiation process. We aim to find a therapeutic target in redifferentiation strategies for thyroid cancer.
Methods: Our study integrated the differentially expressed genes acquired from the Gene Expression Omnibus database by comparing TSHR expression leve… Show more
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