Targeting the epigenetically older individuals for geroprotective trials: the use of DNA methylation clocks

Abstract

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Accelerated Aging in Cancer Survivors: Cellular Senescence, Frailty, and Possible Opportunities for Interventions

“…Most aging clocks were trained against chronological age or mortality. Aging clocks can be used to identify individuals whose biological age is higher than their chronological age (the positive deviation is called age acceleration) [ 44 ] and predict their future risk of mortality and age-related diseases.…”